Modeyso (Dordaviprone)

 Modeyso (dordaviprone) is a protease activator used for the treatment of adult and pediatric patients aged 1 year and older with diffuse midline glioma harboring an H3 K27M mutation with progressive disease following prior therapy.

This indication is approved under accelerated approval based on response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).

Recommended Dosage:
Dosage for Adults: The recommended dosage of Dordaviprone is 625 mg orally once weekly. Take the dosage on an empty stomach (at least 1 hour before or 3 hours after food intake).
Dosage for Children (1 to <17 years old): The dose of Dordaviprone for children depends on their body weight. This medicinal product is not recommended for children who weigh less than 10 kg. Recommended weekly dose by weight:

• 10 to <12.5 kg → 125 mg once a week
• 12.5 to <27.5 kg → 250 mg once a week
• 27.5 to <42.5 kg → 375 mg once a week
• 42.5 to <52.5 kg → 500 mg once a week
• 52.5 kg or more → 625 mg once a week

Continue taking this medicine until the doctor tells you to stop (for example, if the disease gets worse or side effects become too strong). Swallow the oral capsules whole with water.
If your child cannot swallow capsules, open the capsule and mix the contents in 15–30 mL of liquid (such as sports drink, apple juice, lemonade, or water). Give the mixture right away, within 2 hours. If not used in time, throw it away and prepare a new one.

• This medication should not be used by patients who have a history of known hypersensitivity to Dordaviprone or any of its ingredients. There may be severe allergic reactions that cause rash, itching, or trouble breathing. If hypersensitivity symptoms develop during treatment, it is recommended to stop immediately and seek medical attention.
• Dordaviprone may cause QTc interval prolongation, which can increase the risk of irregular heart rhythm. Patients with cardiac history or those on other QT-prolonging drugs require monitoring. Baseline and periodic ECGs are recommended to minimize potential cardiac risks during therapy.
• Use Dordaviprone during pregnancy only if the potential benefit clearly outweighs the possible risk to the fetus. Animal studies indicate developmental toxicity. Women of childbearing age must discuss treatment strategy and precautions with their healthcare provider (HCP) before initiation.
• It is not known whether this medicine passes into human breast milk. Because of potential side effects on infants, avoid breastfeeding during treatment. Mothers should consult their healthcare provider to weigh the benefits of therapy against the risks of exposure for infants.
• Both female and male patients must use effective contraception during treatment and for a period after completion, as advised by their clinician. This precaution helps prevent potential risks to unborn children because of drug-related reproductive toxicity.

What documents are required to import MODEYSO to India?

MODEYSO (dordaviprone) capsules can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is MODEYSO available in India?

MODEYSO (dordaviprone capsules) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

• On availability of Modeyso in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

MODEYSO can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of MODEYSO (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork-in-253190.hostingersite.com for Modeyso Capsules 125 mg price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source MODEYSO (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Modeyso®?

Dordaviprone is the Generic Name for the trade name drug Modeyso®.

What is the Manufacturer’s Name of Modeyso®?

Modeyso® is manufactured by Jazz Pharmaceuticals plc.

Is Modeyso approved by the FDA?

Yes. Modeyso is approved by the FDA. Date of first approval: August 06, 2025.

What is the dosage and form of Modeyso® supplied?

Modeyso is supplied as Capsules: 125 mg for oral administration.

What are the most common side effects of Modeyso® Capsules?

The most commonly reported side effects of Modeyso® are e fatigue, nausea, headache, vomiting, and musculoskeletal pain.

How much does Modeyso® Capsule cost in India?

Modeyso® is not yet approved in India. However, patients in India can legally access it through the provision called the Named Patient Program (NPP). Modeyso prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Modeyso Capsules 125 mg cost in India, please call/WhatsApp +91-9310090915 or send an email to info@indianpharmanetwork-in-253190.hostingersite.com.

Can Modeyso® 125 mg Capsules be available in SAARC countries?

Apart from Gulf countries, Modeyso® can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Modeyso® Capsules in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Modeyso® Capsules online in India?

Yes, one can buy Modeyso 125 mg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the legal supply of Modeyso® Capsules through legal channels.

What are the storage conditions of Modeyso® 125 mg Capsules?

Store this therapeutic drug at 20°C to 25°C (68°F to 77°F); excursions permitted from 15°C to 30°C (59°F to 86°F).