- Medicine Name: Onpattro
- Generic Name: Patisiran
- Dosage Form & Strength: Lipid Complex Injection: 10 mg/5 mL (2 mg/mL) in a single-dose vial
- Manufactured By: Alnylam Pharmaceuticals, Inc.
Onpattro contains a transthyretin-directed small interfering RNA and is used for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adult patients.
Recommended Dosage: Onpattro comes as a liquid in a single-dose vial and should be administered by a health specialist. It is administered via intravenous (IV) infusion. Dosage of Onpattro injection depends on the actual body weight.
For patients weighing less than 100 kg, the recommended dose of Onpattro is 0.3 mg/kg given once every 3 weeks.
For patients weighing 100 kg or more, the recommended dose of Onpattro is 30 mg given once every 3 weeks.
Missed Dose: If a dose is missed, administer as quickly as possible.
- If Onpattro is used within 3 days of the missed dose, continue dosing according to the patient’s original schedule.
- If Onpattro is used more than 3 days after the missed dose, continue dosing every 3 weeks thereafter.
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