Olverembatinib

Olverembatinib is an oral, third-generation BCR-ABL1 tyrosine kinase inhibitor (TKI), approved and marketed in China for the treatment of:

• Adult patients with TKI-resistant chronic-phase CML (CP-CML) harboring the T315I mutation
• Adult patients with accelerated-phase CML (AP-CML) harboring the T315I mutation
• Adult patients with chronic-phase CML resistant to and/or intolerant of first- and second-generation TKIs

This therapeutic drug is particularly relevant in patients where prior TKI therapies have either failed or are not tolerated.

Recommended Dosage:
The recommended dosage should always be determined by the treating oncologist based on clinical evaluation. Typical dosing (as per approved labeling in China) is 40 mg orally once every other day or as prescribed by the treating physician. Dose adjustments may be required depending on response and tolerability

Tablets should be swallowed whole with water. Do not crush, chew, split, or dissolve the tablets before administration. Olverembatinib may be taken with or without food, unless otherwise directed by the treating physician. Continue treatment until there is evidence of disease progression or unacceptable toxicity.

Dosage can be modified in cases of hematologic and non-hematologic toxicities as detailed in the prescribing information. If a dose is missed, patients should follow their doctor’s guidance and should not double the next dose.

• This medicine may cause severe decreases in platelets, neutrophils, and hemoglobin, leading to bleeding, infections, or anemia. Complete blood counts should be checked regularly before and during treatment. Dose interruption or adjustment may be required if significant blood abnormalities develop.
• Elevations in liver enzymes such as ALT, AST, and bilirubin may occur during treatment. Liver function tests should be performed before starting therapy and monitored regularly. Treatment interruption, dose reduction, or discontinuation may be necessary if severe liver abnormalities develop.
• This medicine may increase blood pressure or worsen existing hypertension. Blood pressure should be controlled before starting treatment and monitored regularly during therapy. If significant hypertension occurs, appropriate medical management and possible dose adjustment may be required.
• Arrhythmias, palpitations, and other cardiac effects have been reported in some patients. Patients with existing heart conditions should be monitored carefully. An electrocardiogram (ECG) assessment may be required during treatment to detect and manage potential cardiac abnormalities.
• Peripheral edema and fluid accumulation may occur during treatment. Patients should be monitored for swelling, sudden weight gain, or shortness of breath. Medical evaluation is recommended if significant fluid retention develops, and treatment adjustment may be necessary.
• This medicine may increase sensitivity to sunlight and cause skin reactions. Patients should avoid excessive sun exposure and use protective clothing and sunscreen while outdoors. If severe skin reactions occur, medical advice should be sought promptly.
• This medicine may cause harm to an unborn baby. Women of childbearing potential must use effective contraception during treatment and for at least four months after the last dose. If pregnancy occurs, immediate medical consultation is required.
• It is not known whether this medicine passes into breast milk, but the potential risk to infants cannot be excluded. Breastfeeding is not recommended during treatment and for at least seven days after the final dose. Consult a healthcare provider before resuming breastfeeding.

What documents are required to import Olverembatinib to India?

Olverembatinib tablets can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is Olverembatinib available in India?

Olverembatinib tablet is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

• On the availability of Olverembatinib in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Olverembatinib price in India.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

Olverembatinib can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of Olverembatinib (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact +91-9810469557 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Olverembatinib cost in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source Olverembatinib (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

Is Olverembatinib the generic name of the drug?

Olverembatinib is the generic name of the drug and also refers to its active pharmaceutical ingredient (API). The generic name identifies the core medicinal substance responsible for its therapeutic effect.

What is the Manufacturer’s Name of Olverembatinib®?

Olverembatinib® is manufactured by Ascentage Pharma.

Is Olverembatinib approved by the FDA?

As of the current regulatory status, Olverembatinib was approved by China’s NMPA in November 2021. It is not approved by the US FDA.

What is the dosage and form of Olverembatinib® supplied?

Olverembatinib is supplied as Tablets: 10 mg for oral use.

What are the most common side effects of Olverembatinib® Tablets?

The most commonly reported side effects of Olverembatinib® are thrombocytopenia (low platelet count), anemia, neutropenia, hypertriglyceridemia, elevated liver enzymes, hyperuricemia, hypertension, skin pigmentation, fatigue, headache, rash, edema, and musculoskeletal pain.

How does Olverembatinib Import in India work?

Olverembatinib import in India is possible through the Named Patient Program. This means the medicine can be imported for a specific patient with a valid doctor’s prescription. Indian Pharma Network helps manage the complete process, including approvals and delivery, making sure the medicine reaches the patient safely and legally.

How much does Olverembatinib® Tablet cost in India?

Olverembatinib® is not yet approved in India. However, patients in India can legally access it through the provision called the Named Patient Program (NPP). Olverembatinib prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Olverembatinib cost in India, please call/WhatsApp +91 98104 69557 or send an email to info@indianpharmanetwork.in.

Can Olverembatinib® Tablets be available in SAARC countries?

Apart from Gulf countries, Olverembatinib® can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Olverembatinib® Tablets in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Olverembatinib® Tablets online in India?

Yes, one can buy Olverembatinib in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the supply of Olverembatinib® Tablets through legal channels.

What are the storage conditions of Olverembatinib® Tablets?

Store the tablets below 25°C.