Pheburane (Sodium Phenylbutyrate)

Pheburane (sodium phenylbutyrate) is a nitrogen-binding agent indicated as adjunctive therapy to standard of care, which includes dietary management, for the chronic management of adult and pediatric patients with urea cycle disorders (UCDs), involving deficiencies of carbamylphosphate synthetase (CPS), ornithine transcarbamylase (OTC), or argininosuccinic acid synthetase.

Limitations of Use: This therapeutic drug is not indicated for the treatment of acute hyperammonemia.

Recommended Dosage:
The recommended dosage of Pheburane (measured as sodium phenylbutyrate) for patients with urea cycle disorders is:

• Patients weighing less than 20kg: 450 – 600 mg/kg/day of sodium phenylbutyrate orally. Divide the calculated total daily dose into three to six doses. Administer three to six divided doses and take with food.
• Patients weighing greater than or equal to 20 kg: 9.9 – 13 g/m2/day of sodium phenylbutyrate orally. Divide the calculated total daily dose into three to six doses. Administer as three to six divided doses and take with food.

The maximum dosage is 20 grams per day. Combine this treatment with dietary protein restriction and, in some cases, amino acid supplementation (e.g., essential amino acids, arginine, citrulline, and protein-free calorie supplements). Measure the dose using only the calibrated spoon provided in the packaging. This calibrated dosing spoon directly measures Pheburane oral pellets as sodium phenylbutyrate.

If a dose is missed, take the missed dose as quickly as possible. There should be at least 3 hours between two doses, and doses should not be doubled to make up for the missed dose.

• High levels of phenylacetate in the blood may cause side effects related to the nervous system, such as headache, confusion, sleepiness, or dizziness. Patients should be monitored regularly, and dose adjustments may be required to reduce the risk of toxicity.
• Treatment with Pheburane may lower potassium levels in the blood, which can cause weakness, muscle cramps, or irregular heartbeat. Regular monitoring of potassium levels is important, and supplementation may be required to maintain normal levels during treatment.
• Use this medicinal product with caution in those who have conditions linked with fluid retention, such as kidney disease, heart failure, or liver problems. The sodium content in the medicine may worsen swelling or fluid buildup in these patients.
• Pheburane contains sucrose, so use it carefully in patients with diabetes or rare sugar-related disorders. These patients may have difficulty processing sugars, which could cause worsening symptoms or complications during treatment.
• There is limited information about the use of this medicine during pregnancy. It should only be used if clearly required and prescribed by a clinician. The potential benefits should outweigh possible risks to the unborn baby.
• It is not known whether Pheburane passes into human breast milk. A decision should be made whether to stop breastfeeding or discontinue treatment, considering the importance of treatment for the mother and the possible risk to the infant.

What documents are required to import PHEBURANE to India?

PHEBURANE (sodium phenylbutyrate) oral pellets can be imported by patients or government hospitals in the name of the patients only.

• The following documentation is required to import the product:
• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is PHEBURANE available in India?

PHEBURANE (sodium phenylbutyrate oral pellets) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

• On the availability of Pheburane in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
  Pheburane price in India.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

PHEBURANE can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, as well as other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of PHEBURANE (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please WhatsApp +91 98104 69557 | Toll-Free Number: 1800-1200-365 or write us at info@indianpharmanetwork.in for the Pheburane cost in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source PHEBURANE (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Pheburane®?

Sodium phenylbutyrate is the Generic Name for the trade name drug Pheburane®.

What is the Manufacturer’s Name of Pheburane®?

Pheburane® is manufactured by Lucane Pharma.

Is Pheburane approved by the FDA?

Yes. Pheburane is approved by the FDA. Date of first approval: June 2022.

What is the dosage and form of Pheburane® supplied?

Pheburane is supplied for oral pellets: 84 g of sodium phenylbutyrate per bottle.

What are the most common side effects of Pheburane® oral pellets?

The most commonly reported side effects of Pheburane® are menstrual dysfunction, body odor, decreased appetite, and bad taste or taste aversion.

How does Pheburane Import in India work?

Pheburane Import in India is possible through the Named Patient Program. This means the medicine can be imported for a specific patient with a valid doctor’s prescription. Indian Pharma Network helps manage the complete process, including approvals and delivery, making sure the medicine reaches the patient safely and legally.

Who is a reliable Pheburane supplier in India?

Indian Pharma Network is a trusted Pheburane supplier in India, facilitating compliant access through global sourcing channels and structured documentation support for eligible patients under applicable regulatory provisions.

How much does Pheburane® oral pellets cost in India?

Pheburane ® is not yet approved in India. However, patients in India can legally access it through the provision called the Named Patient Program (NPP). Pheburane prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Pheburane cost in India, please call/WhatsApp +91 98104 69557 or send an email to info@indianpharmanetwork.in.

Can Pheburane® oral pellets be available in SAARC countries?

Apart from Gulf countries, Pheburane® oral pellets can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Pheburane® oral pellets in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Pheburane® oral pellets online in India?

Yes, one can buy Pheburane in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the supply of Pheburane® oral pellets through legal channels.

Who is an authorized Pheburane® importer in India?

Indian Pharma Network acts as a Pheburane importer in India, assisting with Named Patient import processes, regulatory documentation, and compliant international procurement for patients requiring this therapy.

What are the storage conditions of Pheburane® oral pellets?

Store oral pellets at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F). Discard any remaining medicine 45 days after first opening of the bottle.