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TNKase (Tenecteplase)

  • Medicine Name: TNKase
  • API: Tenecteplase
  • Dosage Form & Strength: For Injection: 25 mg or 50 mg lyophilized powder in a single-dose vial copackaged with Sterile Water for Injection USP (diluent)
  • Manufactured By: Genentech, Inc.

Medical Uses

TNKase (tenecteplase: a modified form of human tissue plasminogen activator (tPA) that works by breaking down fibrin, a component of blood clots) is a tissue plasminogen activator (tPA) used:

  • for the treatment of acute ischemic stroke (AIS) in adults.
  • to reduce the risk of death associated with acute ST elevation myocardial infarction (STEMI) in adults.

Recommended Dosage:
The recommended dosage of TNKase is for intravenous (IV) administration only, administered as a single bolus over 5 seconds.

  • Acute Ischemic Stroke (AIS): Start treatment as promptly as possible and within 3 hours after the onset of stroke symptoms. Individualize the dosage of this therapeutic drug based on the patient’s weight. The maximum recommended dose of TNKase is 25 mg (5 mL).
  • Acute STEMI: Start treatment as promptly as possible after the onset of acute ST elevation myocardial infarction (STEMI) symptoms. Individualize the dosage of this therapeutic drug based on the patient’s weight. The maximum recommended dose of TNKase is 50 mg (10 mL).

Warning & Precautions

  • The use of Tenecteplase 25 mg/50 mg injection has the potential risk of increased bleeding. Take extra precautions with patients who have active bleeding conditions, recent surgery, or have any history of gastrointestinal bleeding. Regular assessments of blood coagulation levels are recommended.
  • Rashes, skin swelling, or even difficulties in breathing can occur due to allergic reactions to Tenecteplase. At any signs of hypersensitivity, treatment with this medicine should be stopped immediately, and appropriate measures need to be taken during treatment.
  • There is a possibility of having thromboembolic events when Tenecteplase is used, which necessitates caution for patients who have a history of going through arterial or venous thromboembolism. It is highly important to monitor the patient for any complications.
  • On rare occasions, this therapeutic drug can be responsible for causing cholesterol embolization. This may lead to organ damage. Signs and symptoms may include abdominal pain, fever, or skin discoloration. Stop treatment with this medicine and provide supportive care if this occurs.
  • Additionally, patients encountering heart diseases may find Tenecteplase triggering arrhythmias. For this reason, there is a need to monitor the heart for any unexpected rhythms or rate changes and ensure constant cardiac supervision throughout the treatment.
  • Tenecteplase 25 mg/50 mg injection is classified as pregnancy category C. Do not use this medicinal product during pregnancy if the potential benefit outweighs the risks. Consult a healthcare provider (HCP) before use in pregnant women to evaluate the potential for harm to the fetus.
  • There is not much information available on the excretion of Tenecteplase in human breast milk. Therefore, if the medication is given to a lactating mother, the appropriate steps should be followed. To avoid the dangers associated with Tenecteplase, its use in breastfeeding should be analyzed critically.

Documentation & Availability

What documents are required to import TNKASE to India?

TNKASE (tenecteplase) injections can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

  • A valid prescription from a qualified doctor.
  • Patients diagnostic reports
  • Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

  • A valid prescription from the Doctor
  • Import permit if applicable

Is TNKASE available in India?

TNKASE (tenecteplase injections) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

  • On availability of TNKase in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
  • On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
  • Medicine Price.
  • Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
  • Ensuring 100% transparency.

TNKASE can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of TNKASE (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for TNKase 25 mg/50 mg injection price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Sourcing & Delivery

Indian Pharma Network can source TNKASE (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

FAQ

What is the Generic Name for the trade name drug TNKase®?

Tenecteplase is a Generic Name for the trade name drug TNKase®.

What is the Manufacturer's Name of TNKase®?

TNKase® is manufactured by Genentech, Inc.

Is TNKase approved by the FDA?

Yes, TNKase® is approved by the FDA. Date of first approval: June 2, 2000.

What is the dosage and form of TNKase® supplied?

TNKase is supplied for Injection: 25 mg or 50 mg lyophilized powder in a single-dose vial, copackaged with sterile water for injection USP (diluent) for intravenous (IV) use.

What are the most common side effects of TNKase® 25 mg/50 mg injections?

The most common side effect of TNKase® injection is bleeding.

How much does TNKase® 25 mg/50 mg injection cost in India?

Prices of TNKase injections may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest TNKase 25 mg/50 mg cost in India, please call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can TNKase® 25 mg/50 mg injections be available in SAARC countries?

Apart from Gulf countries, TNKase® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of TNKase® injections in these countries. We help ensure legal access to this therapeutic drug through our reliable channels.

Is it safe to buy TNKase® 25 mg/50 mg injections online in India?

Yes, one can buy TNKase 25 mg/50 mg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the legal supply of TNKase® injections through legal channels.

What are the storage conditions of TNKase® 25 mg/50 mg injections?

Store lyophilized TNKase at room temperature up to 30°C (86°F) or refrigerated at 2 to 8°C (36 to 46°F). Never use any medicine beyond the expiration date mentioned on the vial.

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