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Triokris (Trientine Hydrochloride)

  • Brand Name: Triokris™
  • Active Ingredient: Trientine Hydrochloride USP
  • Strength: 250 mg Capsules
  • Packaging: 100 Capsules per Bottle
  • Manufacturing: US FDA–Approved Facility in India
  • Company: Ikris Pharma Network Pvt Ltd
  • Country of Origin: India

Medical Use

Trientine (trientine hydrochloride) is prescribed for the treatment of Wilson’s disease, particularly for patients who are unable to tolerate penicillamine. Wilson’s disease is characterized by an abnormal accumulation of copper in the body. Unlike penicillamine, this therapeutic drug is not suitable for the treatment of cystinuria or rheumatoid arthritis, as it is ineffective for these conditions.

Recommended Dosage: The initial recommended dosage of Trientine for pediatric patients is 500 to 750 mg/day, while for adults, it’s 750 to 1250 mg/day. This dosage should be divided into two, three, or four doses throughout the day. If necessary, the dose may be gradually increased, with a maximum limit of 2000 mg/day for adults and 1500 mg/day for pediatric patients under the age of 12.

Dose adjustments should only be made if the clinical response is insufficient or if the free serum copper concentration remains consistently above 20 mcg/dL. For long-term treatment, the optimal maintenance dosage should be reassessed every 6 to 12 months.

To ensure proper absorption, take Trientine on an empty stomach—either at least one hour before meals or two hours after. Additionally, it must be taken at least one hour apart from other medications, food, or milk. The capsules must be swallowed whole with water and should not be opened or chewed.

Warning & Precautions

  • Patients with a known allergy to trientine or any of its components should not use Trientine 250 mg. Severe allergic reactions may include rash, itching, swelling, dizziness, and difficulty breathing. Discontinue immediately if hypersensitivity occurs.
  • Trientine may reduce iron levels in the body. Regular monitoring of hemoglobin and serum ferritin is recommended. Supplement with iron only under medical supervision, as iron can interfere with trientine’s effectiveness.
  • Treatment with Trientine should be used during pregnancy only if clearly needed. Animal studies have shown potential risks, and there is limited human data. Caution is also advised if breastfeeding, as it is unknown if the drug is excreted in breast milk.
  • Some patients may experience a worsening of neurological symptoms during treatment with trientine 250 mg capsules. Regular follow-up with a healthcare provider is essential to adjust the dosage if needed.
    Trientine may interact with other medications, particularly those containing iron, zinc, or other metals. Take this therapeutic drug on an empty stomach, at least one hour apart from other medications, to avoid interactions.
  • To ensure the safe and effective use of Trientine, regular monitoring of copper levels, liver function tests, and complete blood counts is essential. This helps in detecting potential side effects and adjusting treatment as needed to maintain optimal health and effectiveness.

Documentation & Availability

Export of Trientine (Triokris™) from India: Triokris™ (Trientine Hydrochloride 250 mg) is now approved and manufactured in a USFDA-approved facility, to the highest standards of safety and quality. India. As a trusted Trientine manufacturer and exporter from India, Indian Pharma Network (IPN) supplies this life-saving medicine to hospitals, distributors, importers, and NGOs across the world.

Trientine is indicated for the treatment of Wilson’s Disease, a rare inherited disorder caused by mutations in the ATP7B gene, leading to excessive copper accumulation in the body. The medicine helps reduce copper levels and prevent liver and neurological damage.

Global Availability:
Ikris Pharma Network exports Trientine (Triokris™) to multiple regions, including:

  • Asia: Cambodia, Philippines, Vietnam, Laos, Thailand, Singapore, Myanmar, Malaysia, Indonesia
  • Africa: Kenya, Nigeria, Somalia, South Sudan, South Africa, Sierra Leone, Mali, Guinea, Gambia, Tanzania, Malawi, Angola, Mozambique, Madagascar, Niger, Chad, DRC, Zambia, Cameroon, Ghana, Togo
  • North America: El Salvador, Nicaragua, Costa Rica, Dominican Republic, Guatemala, Barbados, Guadeloupe, Dominica, Martinique, St Lucia, Jamaica
  • South America: Venezuela, Guyana, Suriname, French Guiana, Chile, Bolivia, Paraguay, Ecuador
    Middle East & Gulf Countries: Kuwait, UAE, Saudi Arabia, Oman, Iraq, Yemen, Iran, Syria, Jordan, Lebanon, Qatar, Bahrain, Egypt, Libya, Tunisia, Algeria, Sudan
    Commonwealth of Independent States (CIS): Tajikistan, Uzbekistan, Turkmenistan, Kazakhstan, Mongolia, Kyrgyzstan, Azerbaijan, Armenia, Georgia
  • Oceania: Australia and New Zealand. Papua New Guinea, Fiji, Solomon Islands, Vanuatu, Tonga, Samoa

We also support export through government tenders, NGOs, hospitals, and pharmaceutical importers under full compliance with export regulations.

Sourcing & Delivery

Indian Pharma Network (IPN) is a WHO-GDP, EU-GDP, and ISO-certified Trientine 250 mg exporter in India. We offer a robust global supply chain for generic Trientine (Triokris™). As a manufacturer and reliable supplier of Trientine 250 mg, we ensure that every shipment meets international quality, temperature control, and regulatory standards.

Our Export Process:

  • Manufacturing & Quality Assurance: Trientine (Triokris™) is manufactured in a US FDA-approved facility following GMP guidelines to ensure the highest quality, purity, and efficacy.
  • Product Documentation & Compliance: Each batch is accompanied by essential export documentation, such as:
  • Certificate of Analysis (COA)
  • Batch Release Certificate
  • Invoice & Packing List
  • Certificate of Origin (COO)
  • Temperature Monitoring Records (if applicable)

Temperature-Controlled Dispatch: IPN maintains the integrity of Trientine through GDP-certified cold chain logistics. Shipments are handled via validated couriers from our logistics hubs in Noida, Belgium, and Bulgaria.
Global Distribution Support: We deliver worldwide via air freight and sea cargo, partnering with WHO-GDP-approved logistic partners for safe and timely deliveries.

IPN (Indian Pharma Network) can facilitate the supply of Trientine (prescription medicines) to all locations in the world and after fulfilling the legal requirements (if applicable).

Please contact us for export enquiries and Trientine 250 mg price in India. For export inquiries or bulk supply of Trientine Hydrochloride 250 mg, call: +91 85272 73611, WhatsApp: +91 98104 69557, dial our Toll-Free: 1800 1200 365, or write us at info@indianpharmanetwork.in.

Indian Pharma Network (IPN) is a trusted manufacturer and global exporter of Trientine (Triokris™) from India. We are delivering quality medicines worldwide with safety, compliance, and care.

FAQ

What is Triokris (Trientine 250 mg)?

Triokris is an Indian generic brand that serves as an alternative to the brand-name medicine Syprine. It contains the active ingredient Trientine Hydrochloride, which is used for the treatment of Wilson’s disease, a rare genetic condition where excess copper accumulates in the liver, brain, and other organs.

Is Triokris (Trientine 250 mg) available for export from India?

Yes, we are a leading Trientine 250 mg exporter from India to various regions worldwide, including Asia, Australia, North America, South America, Central America, Eastern Europe, Western Europe, the Middle East, and Africa.

How can global Importers, Hospitals, or NGOs access Triokris (Trientine 250 mg) from India?

Global importers, hospitals, and NGOs can buy Trientine Hydrochloride 250 mg from India (Triokris™) directly through Indian Pharma Network (IPN) — the manufacturer and global exporter of Trientine from India.

Where can I get Triokris (Trientine 250 mg) at the best Price?

Order generic Trientine at the best price today. We request that you call: +91 85272 73611, WhatsApp: +91 98104 69557, dial our TOLL-FREE Number: 1800 1200 365, or write to us at info@indianpharmanetwork.in. We are fully committed to providing you with the best Trientine 250 mg price from India. That is why we’ll match the cost/price of any other facilitators/suppliers/distributors in the market who require a valid medical prescription.

Is the Triokris (Trientine 250 mg) available in India?

Triokris (Trientine 25 mg) is a generic alternative to Syprine and is available in India. It is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription. A generic Trientine can be made available across the world through India’s authorized distributor network. (Ahmedabad, Mumbai, Pune, Kolkata, Hyderabad, Bangalore, Chennai, Delhi, etc.).

Can You Send the Triokris (Trientine 250 mg) to Foreign Destinations?

Buy generic Trientine online at the lowest price from a leading supplier/exporter. We can assist in the delivery of Trientine capsules; the doctor-prescribed medication to Austria, Belgium, France, Germany, Ireland, Luxembourg, Netherlands, Switzerland, the UK, Israel, Iraq, Jordan, Bahrain, Egypt, Iran, Kuwait, Qatar, Lebanon, Oman, Saudi Arabia, Syria, Turkey, UAE, Belize, Costa Rica, El Salvador, Guatemala, Italy, Czech Republic, Panama, Serbia, Slovakia, Slovenia, Ukraine, Russia, Bulgaria, Croatia, Estonia, Hungary, Kosovo, Latvia, Lithuania, Moldova, Poland, Romania, Belarus, Argentina, Brazil, Chile, Colombia, Guyana, Peru, Ecuador, Paraguay, Suriname, Uruguay, Venezuela, Canada, Mexico, US, Singapore, Japan, Sri Lanka, Indonesia, and China.

What is the procedure for buying Triokris (Trientine 250 mg Capsules) from India?

Patients can simply fill out the order form or send an email to info@indianpharmanetwork.in. Patients can also call: +91 85272 73611, WhatsApp: +91 98104 69557, or dial the TOLL-FREE Number: 1800 1200 365. We will reply ASAP with the details of the Trientine 250 mg price and the procurement procedure.
Note:- The order will be confirmed only after the valid receipt of the prescription from the Physician.

Is it safe to buy Triokris (Trientine hydrochloride) Capsules online from India?

Yes, one can buy Trientine capsules online from India-based Indian Pharma Network (IPN) if the medicinal product is not yet registered or is unavailable in their respective country. We can help facilitate the supply of generic Trientine from India through legal channels.

What are the main export markets for Triokris (Trientine 250 mg Capsules)?

The main export markets for Triokris (Trientine 250 mg capsules) are Western Europe (Austria, Belgium, France, Germany, Ireland, Liechtenstein, Luxembourg, Monaco, Netherlands, Switzerland, United Kingdom, Andorra), Australia, the Middle East (Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, Turkey, UAE, Yemen), Central America (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama), Eastern Europe (Serbia, Slovakia, Slovenia, Ukraine, Russia, Bulgaria, Croatia, Czech Republic, Estonia, Hungary, Kosovo, Latvia, Lithuania, Moldova, Montenegro, North Macedonia, Poland, Romania, Albania, Belarus, Bosnia, Herzegovina), South America (Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Guyana, Paraguay, Peru, Suriname, Uruguay, Venezuela), Asia (Vietnam, Thailand, Singapore, Sri Lanka, Philippines, Maldives, Malaysia, Japan, Indonesia, China, Bangladesh, Bhutan, Afghanistan), North America (Canada, Mexico, US, Cuba, Jamaica, Haiti, and Africa.

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