Cotellic (cobimetinib)
- Drug Name: Cotellic
- Generic Name: Cobimetinib
- Dosage Forms and Strengths: Tablets: 20 mg
- Manufactured by: Genentech
- Treating adult patients with unresectable or metastatic melanoma that has a specific type of genetic mutation (BRAF V600E or V600K). It’s used along with another medicine called vemurafenib.
- Treating adult patients with histiocytic neoplasms as a single medicine.
- To use COTELLIC with vemurafenib for melanoma, doctors check if the patient’s tumor has the right genetic mutation before starting treatment.
Recommended Dosage:
- The recommended dose is 60 mg once daily for 21 days of each 28-day cycle. Take it with or without food until the disease gets worse or if you have side effects that are not okay.
- COTELLIC comes in tablets of 20 mg each.
- Keep an eye out for any new cancers, both on the skin and inside the body, before, during, and even after stopping COTELLIC for about six months.
- Watch for signs of bleeding, as it can happen while taking COTELLIC.
- Be aware of possible heart issues and get regular heart checks during treatment.
- Pay attention to severe skin rashes. If they happen, the doctor might stop or lower the dose of COTELLIC.
- Get your eyes checked regularly, especially if you notice any vision changes. If there are certain eye issues, the doctor might stop COTELLIC permanently.
- Doctors will regularly check your liver function during treatment.
- Watch for signs of muscle problems and report them to your doctor.
- Avoid too much sun exposure and protect your skin while taking COTELLIC.
- Pregnant women or those planning to get pregnant should use effective birth control methods as COTELLIC can harm an unborn baby.
- A valid prescription from a qualified medical practitioner.
- Diagnostic reports of the patient.
- Government-issued identification proof for the patient, as recognized by the Government of India.
- A valid prescription from a qualified doctor.
- An import permit, if applicable.
Indian Pharma Network is proficient in sourcing Cotellic (cobimetinib) from around the world and ensuring efficient delivery to patients. We provide worldwide access to the best available treatments and expedite prescription dispensing and delivery, with all prescriptions being dispensed and scrutinized by registered pharmacists before dispatching them to the patient’s address, exclusively from New Delhi, India.
How does Cotellic work in treating melanoma?
Cotellic, containing cobimetinib, operates by specifically targeting mutated proteins within cancer cells. It blocks the activity of a protein involved in cancer cell growth (BRAF V600 mutation), hindering the spread of melanoma. This combination treatment helps stop the growth and spread of cancer cells.
Can Cotellic be used as a standalone treatment for melanoma?
Cotellic, as a single-agent therapy, is approved for treating histiocytic neoplasms, a type of cancer involving certain white blood cells. However, its application in melanoma specifically requires combination therapy with another medication called vemurafenib to effectively treat melanoma patients with a BRAF V600 mutation.
How long should patients take Cotellic for the treatment of melanoma?
The recommended duration of Cotellic treatment varies. Patients usually take it orally once daily for 21 days in a 28-day cycle until they experience disease progression or encounter intolerable side effects. The treatment plan should be determined in consultation with the healthcare provider.
What steps are necessary before starting Cotellic treatment?
Before initiating Cotellic with vemurafenib for treating melanoma, it’s crucial to confirm the presence of the BRAF V600E or V600K mutation in the tumor tissue. This confirmation is essential for the effectiveness of the treatment.
Are there specific side effects to watch for during Cotellic treatment?
Contact Patient Support
If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.
Disclaimer
All Trademarks and Brands that appear on the website belong to their respective owners and indianpharmanetwork does not lay any claim on them we only provide Information.