Cyanokit (Hydroxocobalamin)

Cyanokit (hydroxocobalamin) is an antidote used to treat known or suspected cyanide poisoning, for example in people who have inhaled smoke from house or industrial fires, or who have swallowed or been exposed to cyanide. The usual adult starting dose is 5 g given by intravenous infusion over 15 minutes, which can be repeated depending on the severity of poisoning.

Hydroxocobalamin binds cyanide ions to form cyanocobalamin (vitamin B12), a non-toxic compound that is excreted in the urine. This removes cyanide from the body’s cells and allows normal cellular respiration to resume.

• It causes a temporary red discolouration of the skin, mucous membranes and urine; urine may stay red for several weeks.
• The red colour can interfere with some laboratory tests and may trigger blood-leak alarms on haemodialysis machines.
• Blood pressure may rise during infusion; allergic reactions and kidney injury (including oxalate nephropathy) have been reported, so kidney function should be monitored.
• Treatment should not be delayed while waiting for confirmation of cyanide levels.

Documents required for Cyanokit

Patients and hospitals can import Cyanokit on a named-patient basis. Please keep these ready:

• A valid prescription from a registered emergency physician or toxicologist
• Hospital note documenting suspected or confirmed cyanide poisoning
• Patient ID proof issued by the Government of India

Is Cyanokit available in India?

Cyanokit is an imported medicine and is not readily available through regular pharmacies in India. It can still be accessed legally on a named-patient basis, subject to Indian import regulations.

When will my order be confirmed?

We confirm the order after the prescription has been checked and verified.

Indian Pharma Network imports Cyanokit on request for patients, treating doctors and hospitals, using authorised supply channels only.

Contact us at +91-9310090915 or info@indianpharmanetwork.in for a quote and lead time for Cyanokit in India.

Global Approval Status:

• United States: FDA-approved in December 2006.
• European Union: Authorised in 2007.

What is Cyanokit used for?

Cyanokit (hydroxocobalamin) is a cyanide antidote used for known or suspected cyanide poisoning.

Who manufactures Cyanokit?

Cyanokit is from SERB Pharmaceuticals (originally developed by Merck Santé).

How does Cyanokit work?

Hydroxocobalamin binds cyanide ions to form cyanocobalamin (vitamin B12), a non-toxic compound that is excreted in the urine.

Why does Cyanokit turn the skin and urine red?

Hydroxocobalamin is a deep red compound; the colour is expected and fades over days to weeks.

Is Cyanokit approved by the US FDA?

Yes. Cyanokit is FDA-approved for the treatment of known or suspected cyanide poisoning.