Egaten (Triclabendazole)

Egaten (triclabendazole) is an anti-parasitic medicine used to treat fascioliasis, an infection of the liver and bile ducts caused by the liver flukes Fasciola hepatica and Fasciola gigantica, in patients aged 6 years and older. People are usually infected by eating raw watercress or other water plants contaminated with the parasite.

Triclabendazole is absorbed and converted to active metabolites that are taken up by the flukes and disrupt their microtubules and energy metabolism, killing both immature and adult forms. The approved dose is two doses of 10 mg/kg given 12 hours apart with food.

• Dying parasites can cause abdominal pain and biliary colic, sometimes with jaundice.
• QT prolongation was seen in animal studies; ECG monitoring is advised in patients with a history of QT prolongation or taking QT-prolonging medicines.
• Other common side effects include sweating, nausea, decreased appetite, headache and itching.
• Take with food to improve absorption.

Documents required for Egaten

Patients and hospitals can import Egaten on a named-patient basis. Please keep these ready:

• A valid prescription from a registered infectious disease specialist or gastroenterologist
• Stool, serology or imaging report confirming fascioliasis
• Patient ID proof issued by the Government of India

Is Egaten available in India?

Egaten is an imported medicine and is not readily available through regular pharmacies in India. It can still be accessed legally on a named-patient basis, subject to Indian import regulations.

When will my order be confirmed?

We confirm the order after the prescription has been checked and verified.

Indian Pharma Network imports Egaten on request for patients, treating doctors and hospitals, using authorised supply channels only.

Contact us at +91-9310090915 or info@indianpharmanetwork.in for a quote and lead time for Egaten in India.

Global Approval Status:

• United States: FDA-approved on 13 February 2019 — the first FDA-approved treatment for fascioliasis.
• WHO: Listed as an essential medicine; Novartis has donated triclabendazole to WHO since 2005.

What is Egaten used for?

Egaten (triclabendazole) is a benzimidazole anthelmintic used for fascioliasis (liver fluke infection).

Who manufactures Egaten?

Egaten is from Novartis.

How does Egaten work?

Triclabendazole is absorbed and converted to active metabolites that are taken up by the flukes and disrupt their microtubules and energy metabolism, killing both immature and adult forms.

How long is the course of Egaten?

The approved regimen is just two doses taken 12 hours apart.

Is Egaten approved by the US FDA?

Yes. Egaten was approved by the FDA in February 2019 for fascioliasis in patients 6 years and older.