Estring (Estradiol)

Estring is a soft vaginal ring that treats moderate to severe symptoms of vaginal and vulvar atrophy after menopause, such as dryness, burning, itching and pain during intercourse. In the UK it is licensed for atrophic vaginitis caused by oestrogen deficiency in postmenopausal women.

The ring sits in the upper vagina and releases about 7.5 micrograms of estradiol a day for 90 days, acting on the local tissues. Some estradiol does reach the bloodstream, but less than with oestrogen tablets or patches. The patient leaflet says it takes about 2–3 weeks for the tissues to recover.

• Oestrogens carry risks that include endometrial cancer, stroke, blood clots, breast cancer and dementia. Exposure with Estring is lower than with oral oestrogens, but these warnings still appear in the label. Use it at the lowest effective dose for the shortest time; the UK label caps continuous use at 2 years.
• Any unexpected vaginal bleeding should be reported and checked promptly.
• Not for women with breast cancer or another oestrogen-dependent cancer, unexplained genital bleeding, a past or current blood clot, stroke or heart attack, a known clotting disorder, or liver disease.
• The ring can slip down or come out, for example when straining on the toilet. Rinse it in lukewarm water and put it back.

Can Estring be imported to India?

Yes. When a gynaecologist prescribes Estring and it cannot be bought locally, it can be imported in the patient’s name through the named-patient route.

How many rings should I order?

Each carton contains one ring in a sealed foil pouch, and one ring lasts 3 months. A 6-month supply is therefore 2 rings, and a year is 4. There is only one strength, so the doctor only needs to state the number of rings.

What documents do we need?

• A prescription from a gynaecologist stating the number of rings
• A short clinical note confirming postmenopausal vaginal atrophy
• Government-issued photo ID of the patient

We confirm the order only after the prescription has been checked.

How should Estring be stored?

At room temperature (the US label says 15–25 °C; the UK label says below 25 °C), in its sealed pouch until use. A used ring still contains hormone, so put it back in its pouch or a sealed bag before throwing it away. Do not flush it.

Estring is a small, room-temperature item, so it travels easily. We source it from authorised distributors and check that the expiry date leaves enough time for the 90-day wear period.

For Estring price in India and delivery time, call +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• United States: FDA-approved in 1996 (Pfizer); the label was last updated in February 2026.
• United Kingdom and EU countries: Authorised (Pfizer), for example in the UK and France.

Sources:

• Estring US Prescribing Information (FDA, revised February 2026)
• Estring label on DailyMed (US National Library of Medicine)
• Estring 7.5 micrograms/24 hours – UK SmPC (Pfizer, eMC)

Information last checked: October 2026.

What is Estring (Estradiol) prescribed for?

Estring is a low-dose estradiol vaginal ring indicated for moderate to severe symptoms of vulvar and vaginal atrophy due to menopause.

Who markets Estring?

Estring comes from Pfizer.

How often is Estring changed?

Each ring stays in for 90 days and is then replaced with a new one. Leaving it in longer does not give extra benefit, because the ring releases less and less estradiol.

How does Estring help?

The ring sits in the upper vagina and releases about 7.5 micrograms of estradiol a day for 90 days, acting on the local tissues.

Does Estring have to be removed for sex?

No. The label says the ring does not need to be removed for intercourse. If either partner finds it uncomfortable, it can be taken out beforehand, rinsed and put back afterwards.

Has Estring been approved by the FDA?

Yes. Estring is FDA-approved for moderate to severe symptoms of vulvar and vaginal atrophy due to menopause.