Humatin (Paromomycin Sulfate)

Humatin (paromomycin) is used to treat acute and chronic intestinal amoebiasis, a bowel infection caused by Entamoeba histolytica. It is also used alongside other treatment in hepatic coma (hepatic encephalopathy), to cut down the gut bacteria that produce ammonia. It does not work for amoebic infection outside the bowel, such as a liver abscess.

Paromomycin is an aminoglycoside that stops bacteria making proteins by binding to their ribosomes. Taken by mouth it is hardly absorbed, and almost all of it passes out in the stool, so it acts directly inside the bowel. For amoebiasis the US dose is 25–35 mg per kg a day, split into three doses with meals, for 5 to 10 days.

• Do not use in intestinal obstruction, or in anyone allergic to paromomycin.
• If the bowel lining is ulcerated, more of the drug can be absorbed, which can harm the kidneys. The German label also advises hearing checks in patients with kidney problems, bowel ulcers or long treatment.
• Nausea, abdominal cramps and diarrhoea have been reported, mainly at doses above 3 g a day.
• Long use can allow other germs, including fungi, to overgrow.

Can Humatin be imported to India?

Yes. If your doctor prescribes Humatin and it cannot be supplied locally, it can be imported in your name under the named-patient route.

How many capsules should be ordered?

The dose depends on body weight. For example, a 50 kg adult on 35 mg/kg a day needs 1,750 mg, which is 7 capsules a day. Pack sizes differ by country: 100 capsules per bottle in the US, 16 in Italy and 28 in Germany. Please ask the doctor to write the daily dose and the number of days, and we will work out the packs.

What documents do we need?

• A prescription from a gastroenterologist, infectious disease specialist or physician, with the daily dose and number of days
• A stool test report confirming intestinal amoebiasis, or a clinical note for hepatic encephalopathy
• Government-issued photo ID of the patient

We confirm the order only after the prescription has been checked.

How should Humatin be stored?

The US label says 20–25 °C in a tightly closed container, protected from moisture.

Humatin is available from more than one country, so we compare US and European supply and quote whichever is quicker for the course you need. IPN sources it only through authorised distributors.

For Humatin price in India and delivery time, call +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• United States: FDA-approved; Humatin capsules are currently marketed by Waylis Therapeutics.
• Europe: Authorised in Germany and Italy (Pfizer).

Sources:

• Humatin (paromomycin sulfate) US label on DailyMed (Waylis Therapeutics, revised 10/2025)
• Humatin capsules – German prescribing information (Pfizer Pharma GmbH, November 2023)

Information last checked: October 2026.

What does Humatin treat?

It is an oral aminoglycoside antibiotic, prescribed for intestinal amoebiasis and as an adjunct in hepatic coma.

Which company makes Humatin?

Waylis Therapeutics (US); Pfizer (Germany and Italy).

Does Humatin treat amoebic liver abscess?

No. It acts only inside the bowel and is not effective for amoebiasis outside the intestine.

What is the mechanism of Humatin?

Paromomycin is an aminoglycoside that stops bacteria making proteins by binding to their ribosomes.

Should Humatin be taken with food?

Yes. For intestinal amoebiasis, the US label gives the daily dose in three parts taken with meals.

Does Humatin have FDA approval?

Yes. Humatin (paromomycin sulfate) capsules are FDA-approved for intestinal amoebiasis and as an add-on treatment in hepatic coma.