Taloxa (Felbamate)

Taloxa (felbamate) is used in Europe as an add-on treatment for Lennox-Gastaut syndrome in patients aged 4 and over, when the seizures are not controlled by other suitable antiepileptic medicines. It is never a first choice, and the label asks doctors to reassess whether it is working after 2–3 months. In the US, felbamate (Felbatol) is also approved for partial seizures in adults who have not responded to other treatments.

The exact way felbamate controls seizures is not known; the European label states that it is not an NMDA antagonist. The dose is built up slowly over several weeks, and when it is started the doses of other antiepileptics such as carbamazepine, phenytoin or valproate are usually reduced by 20–30%.

• Felbamate can cause aplastic anaemia (bone marrow failure), seen in about 1 in 4,000 treated patients and fatal in about 30% of cases. It can appear 2–12 months after starting, and the risk can continue after stopping.
• Acute liver failure has also been reported. A full blood count with platelets and liver tests are needed before starting and then every 2 weeks.
• Not for anyone with a history of blood or liver disorders.
• Report bruising, bleeding, signs of infection, yellowing of the skin or eyes, loss of appetite or abdominal pain to the doctor at once.

Can Taloxa be imported for a patient in India?

Yes. For a patient with Lennox-Gastaut syndrome whose neurologist has decided that felbamate is needed, Taloxa can be imported in the patient’s name under the named-patient route.

Tablets or suspension – which should be ordered?

Taloxa comes as 600 mg tablets and as an oral suspension of 600 mg per 5 mL. The suspension comes with a 5 mL oral syringe marked in 0.1 mL steps, which suits weight-based dosing in children. Once a bottle is opened it must be used within one month, so the order should match the dose. The neurologist should state the form and the daily dose.

What documents do we need?

• A prescription from a neurologist stating the form, daily dose and quantity
• A neurologist’s report confirming Lennox-Gastaut syndrome and the medicines already tried
• A recent blood count and liver test report
• Government-issued photo ID of the patient

We confirm the order only after the prescription has been checked.

How should Taloxa be stored?

Below 25 °C. Keep the tablets in the outer carton. Keep the suspension bottle tightly closed and shake it well before each dose.

Because felbamate needs blood and liver tests every two weeks, we make sure the treating neurologist is involved before we source it. IPN obtains Taloxa from authorised European distributors and imports it in the patient’s name.

For Taloxa price in India and delivery time, call +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• European Union: Taloxa tablets and oral suspension are authorised nationally (Organon), for example in France since 1994.
• United States: Felbamate was FDA-approved in July 1993 as Felbatol (now a Viatris product).

Sources:

• Taloxa 600 mg/5 mL oral suspension – French SmPC (base de données publique des médicaments)
• Taloxa 600 mg tablets – French SmPC
• Felbatol (felbamate) US label on DailyMed (Viatris)

Information last checked: October 2026.

What is Taloxa used for?

Taloxa (felbamate) is an antiepileptic medicine used for Lennox-Gastaut syndrome not controlled by other antiepileptics.

Who manufactures Taloxa?

Taloxa is from Organon (in the US the same medicine is sold as Felbatol by Viatris).

How does Taloxa work?

The exact way felbamate controls seizures is not known; the European label states that it is not an NMDA antagonist.

Why is felbamate kept for difficult epilepsy only?

Because of the risk of aplastic anaemia and liver failure, it is used only when safer medicines have not controlled the seizures and the benefit is judged to outweigh the risk.

How often are blood tests needed on Taloxa?

The European label asks for a full blood count with platelets and liver tests before starting and then every 2 weeks for as long as felbamate is taken.

Is Taloxa approved by the US FDA?

Taloxa itself is a European brand. The same medicine, felbamate, is FDA-approved in the US under the name Felbatol.