Xphozah (Tenapanor) Tablets

Xphozah (tenapanor), from Ardelyx, is indicated to reduce serum phosphorus in adults with chronic kidney disease on dialysis, as an add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy.

Tenapanor is a sodium/hydrogen exchanger 3 (NHE3) inhibitor. By inhibiting NHE3 in the gut, it reduces the paracellular absorption of dietary phosphate, helping to lower serum phosphorus levels in dialysis patients.

• Diarrhea is the most common side effect and can be severe in some patients; dose adjustment or discontinuation may be needed.
• Should be used with caution in patients with a history of severe gastrointestinal conditions.
• Not recommended for use in pediatric patients due to risk of dehydration.
• Should be taken immediately prior to or with the first bite of a meal.

What documents are required to import Xphozah to India?

Xphozah may be imported in the patient’s name only, by patients or government hospitals. The following documentation is required:

• A valid prescription from a registered nephrologist
• Diagnostic report confirming chronic kidney disease and dialysis status
• Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription.

Is Xphozah available in India?

Xphozah is not commercially marketed in India. It can be legally accessed through the Named Patient Program (NPP).

Indian Pharma Network (IPN) can source Xphozah from its authorized distribution network and facilitate supply to patients, doctors, and hospitals under applicable legal provisions.

For Xphozah cost in India and availability, contact IPN at Phone: +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• United States: Approved by the FDA — October 2023.

What is Xphozah used for?

Xphozah reduces serum phosphorus in dialysis patients with chronic kidney disease, as an add-on to phosphate binder therapy.

Who manufactures Xphozah?

Xphozah is developed by Ardelyx.

How is Xphozah taken?

As an oral tablet, twice daily immediately before or with meals.

How much does Xphozah cost in India?

Cost depends on monthly quantity and sourcing logistics — share your prescription with IPN for a quote.