YEZTUGO (Lenacapavir) Injection

YEZTUGO (lenacapavir), from Gilead Sciences, is indicated for HIV-1 pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV in at-risk adults and adolescents.

Lenacapavir is a capsid inhibitor that interferes with multiple steps of the HIV-1 replication cycle by disrupting the viral capsid structure, offering long-acting protection with infrequent dosing compared to daily oral PrEP options.

• Must only be used in individuals confirmed HIV-negative immediately prior to initiation and periodically during use.
• Injection-site reactions, including nodules and induration, are commonly reported and can persist for months given the drug’s long-acting depot formulation.
• Risk of hepatitis B virus reactivation in patients with chronic HBV infection.
• Requires administration by a healthcare professional; missed subsequent doses require prompt follow-up per the dosing schedule.

What documents are required to import YEZTUGO to India?

YEZTUGO may be imported in the patient’s name only, by patients or government hospitals. The following documentation is required:

• A valid prescription from a registered physician
• Recent HIV-negative test confirmation as required per label
• Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription and HIV-negative status.

Is YEZTUGO available in India?

YEZTUGO is not commercially marketed in India. It can be legally accessed through the Named Patient Program (NPP).

Indian Pharma Network (IPN) can source YEZTUGO from its authorized distribution network and facilitate supply to patients, doctors, and hospitals under applicable legal provisions.

For YEZTUGO cost in India and availability, contact IPN at Phone: +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• United States: Approved by the FDA — June 2025.

What is YEZTUGO used for?

YEZTUGO is used for HIV-1 pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV.

Who manufactures YEZTUGO?

YEZTUGO is developed by Gilead Sciences.

How is YEZTUGO administered?

By subcutaneous injection, administered twice yearly by a healthcare professional.

How much does YEZTUGO cost in India?

Cost depends on dosing schedule and sourcing logistics — contact IPN for a quote.