Medical Uses
Emcyt (estramustine phosphate sodium), from Pfizer, is an oral estrogen-chemotherapy hybrid agent indicated for the palliative treatment of patients with metastatic and/or progressive carcinoma of the prostate.
Estramustine phosphate combines an estrogen (estradiol) with a nitrogen mustard alkylating agent. It concentrates in prostate tissue and is thought to act primarily through binding to microtubule-associated proteins, disrupting cell division, along with hormonal (anti-androgenic) effects.
