Medical Uses
JASCAYD (nerandomilast), from Boehringer Ingelheim, is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) in adults — the first new IPF treatment approved in over a decade.
Nerandomilast is an oral phosphodiesterase 4B (PDE4B) inhibitor with antifibrotic and immunomodulatory effects. By selectively inhibiting PDE4B, it reduces the expression of pro-fibrotic growth factors and inflammatory cytokines that are overexpressed in pulmonary fibrosis, aiming to slow disease progression.
