JYLAMVO (Methotrexate) Oral Solution

JYLAMVO (methotrexate oral solution) is a ready-to-use liquid formulation of methotrexate indicated for the treatment of severe active rheumatoid arthritis in adults, and polyarticular juvenile idiopathic arthritis, as well as severe, recalcitrant, disabling psoriasis in adults not adequately responsive to other therapies. It is also used in certain oncology protocols under specialist supervision.

Methotrexate is a folate antagonist that inhibits dihydrofolate reductase, interfering with DNA synthesis and cell replication. In rheumatologic and dermatologic conditions, it also has immunomodulatory and anti-inflammatory effects at low weekly doses. JYLAMVO’s oral solution format allows precise, flexible dosing compared with tablets.

• Methotrexate carries serious risks including bone marrow suppression, liver toxicity, and lung toxicity; regular blood counts and liver function monitoring are required.
• Methotrexate is dosed once weekly for rheumatologic/dermatologic use — dosing errors (accidental daily dosing) can be fatal; strict adherence to the prescribed schedule is essential.
• Contraindicated in pregnancy; effective contraception is required for both patients and partners.
• Folic acid supplementation is often prescribed alongside methotrexate to reduce side effects.
• Common side effects: nausea, stomatitis, fatigue, elevated liver enzymes.

What documents are required to import JYLAMVO to India?

JYLAMVO may be imported in the patient’s name only, by patients or government hospitals. The following documentation is required:

• A valid prescription from a registered rheumatologist/dermatologist/oncologist specifying weekly dosing
• Diagnostic report supporting the indication
• Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription and an import permit, if applicable.

Is JYLAMVO available in India?

JYLAMVO is not commercially marketed in India. It can be legally accessed through the Named Patient Program (NPP).

Indian Pharma Network (IPN) can source JYLAMVO from its authorized distribution network and facilitate supply to patients, doctors, and hospitals under applicable legal provisions.

For JYLAMVO cost in India and availability, contact IPN at Phone: +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• European Union: Approved by the EMA.

What is JYLAMVO used for?

JYLAMVO treats severe rheumatoid arthritis, juvenile idiopathic arthritis, and severe psoriasis, and is used in certain oncology protocols.

Who manufactures JYLAMVO?

JYLAMVO is manufactured by Therakind.

How often is JYLAMVO taken for arthritis or psoriasis?

Once weekly — not daily. Always follow your prescriber’s exact schedule, as dosing errors with methotrexate can be dangerous.

How much does JYLAMVO cost in India?

Cost depends on quantity and sourcing logistics — share your prescription with IPN for a quote.