Orladeyo (Berotralstat) 

Orladeyo (berotralstat) is a plasma kallikrein inhibitor indicated for prophylaxis to prevent attacks of hereditary angioedema (HAE) in adults and pediatric patients aged 2 years and older.

Limitations of Use: This therapeutic drug should not be used for the treatment of acute HAE attacks. Additional doses or doses higher than the prescribed once-daily dose are not recommended because of the potential for QTc interval prolongation.

Recommended Dosage:
Recommended Dosage in Adults and Pediatric Patients 12 Years of Age and Older: The recommended dosage of Orladeyo capsules for adults and pediatric patients aged 12 years and older is 150 mg taken orally once daily with food.

Recommended Dosage in Pediatric Patients 2 Years to Less than 12 Years of Age: The recommended dosage of Orladeyo oral pellets for children aged 2 years to less than 12 years depends on the child’s body weight. Capsules should be taken once daily with food, preferably just before or after a meal.

• Children weighing 12 kg to less than 24 kg: 72 mg once daily
• Children weighing 24 kg to less than 32 kg: 96 mg once daily
• Children weighing 32 kg to less than 40 kg: 108 mg once daily
• Children weighing 40 kg or more: 132 mg once daily

Take the capsules of Orladeyo orally with food (a meal should be consumed just before or after dosing).

• Using Orladeyo above the recommended dosage may increase the risk of QTc interval prolongation, which can potentially trigger serious cardiac arrhythmias. Patients with existing heart conditions, electrolyte imbalances, or concurrent QT-prolonging medications should be monitored carefully during treatment and administration.
• Certain medications may alter the effectiveness or blood concentration of Orladeyo by affecting CYP450 enzymes or drug transport pathways. Healthcare providers should review all prescription medicines, supplements, and herbal products before treatment to minimize interactions, side effects, efficacy, or complications.
• The safety of Orladeyo during pregnancy has not been fully established, and potential risks to the developing fetus cannot be excluded. Pregnant women or those planning pregnancy should consult healthcare professionals to evaluate treatment benefits, possible risks, and appropriate alternatives.
• It is not known whether Orladeyo passes into human breast milk or affects nursing infants. Breastfeeding mothers should discuss potential risks and benefits with their healthcare provider before starting therapy, considering the importance of treatment, infant safety, and feeding options.
• The safety and effectiveness of Orladeyo in pediatric patients below the approved age group have not been fully established. Treatment in children should only occur under specialist supervision, with careful monitoring for adverse reactions, dosage adjustments, growth considerations, and outcomes.

What documents are required to import ORLADEYO to India?

ORLADEYO (berotralstat) capsules may be imported by patients or government hospitals in the patients’ names only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is ORLADEYO available in India?

ORLADEYO (berotralstat capsules) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) facilitates the import of cancer medicines under named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

• On the availability of Orladeyo in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
• Orladeyo price in India.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

ORLADEYO can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of ORLADEYO (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact us at WhatsApp: +91 98104 69557 | Toll-Free Number: 1800-1200-365 or write us at info@indianpharmanetwork.in for Orladeyo cost in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source ORLADEYO (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Orladeyo®?

Berotralstat is the Generic Name for the trade name drug Orladeyo®.

What is the Manufacturer’s Name of Orladeyo®?

Orladeyo® is manufactured by BioCryst Pharmaceuticals, Inc.

Is Orladeyo® approved by the FDA?

Yes. Orladeyo® is approved by the FDA. Date of first approval: December 3, 2020.

What strengths and dosage forms are available for Orladeyo®?

Orladeyo® is available as Capsules: 150 mg, 110 mg, and Oral Pellets: 72 mg, 96 mg, 108 mg, or 132 mg in unit-dose packets for oral administration.

What are the most common side effects of Orladeyo® Capsules?

The most commonly reported side effects of Orladeyo are abdominal pain, diarrhea, back pain, vomiting, and gastroesophageal reflux disease.

What is the availability of Orladeyo near Medanta Hospital in Gurgaon?

Patients receiving treatment near Medanta Hospital can buy Orladeyo through a patient-specific import pathway. With a valid oncologist’s prescription, the treatment can be arranged and delivered directly to the hospital in Gurgaon.

What is the availability of Orladeyo in Bangalore?

Orladeyo in Bangalore is not yet commercially marketed, but patients can still access it through regulated import provisions. Once prescribed by a treating clinician, the medicine is sourced internationally and supplied to the treating hospital.

Is Orladeyo available at HCG Cancer Centre, Bangalore?

Orladeyo may not be routinely stocked in India. However, it can be accessed through a Named Patient Program (NPP) with a valid prescription from an oncologist at the hospital. Indian Pharma Network (IPN) can help facilitate the import of Orladeyo at HCG Cancer Centre, Bangalore.

What is the availability of Orladeyo in Mumbai?

The patient can buy Orladeyo in Mumbai via special access programs that allow the import of approved international medicines. The treatment is delivered to the hospital where the patient is undergoing care.

I want to buy Orladeyo in Mumbai. How can I access it?

If you are looking to buy Orladeyo in Mumbai, the first step is consultation with your oncologist. Once prescribed, the medicine can be sourced from global suppliers through a compliant import process and delivered to your treating hospital.

What is the availability of Orladeyo in Chennai?

Patient access to Orladeyo in Chennai is possible through special access programs such as Named Patient Programs (NPP), which allow the import of internationally approved medicines. The treatment is arranged and delivered directly to the hospital where the patient is receiving care, ensuring compliance with regulatory requirements.

I want to buy Orladeyo in Chennai. How can I access it?

If you are looking to buy Orladeyo in Chennai, the first step is to consult your oncologist. Upon prescription, the medicine can be sourced from global suppliers through a compliant import process under NPP and delivered to your treating hospital, such as Apollo Hospitals Chennai or Cancer Institute (WIA).

What is the availability of Orladeyo in Hyderabad?

Orladeyo is accessible in Hyderabad through special access programs like Named Patient Programs (NPP), which enable the legal import of medicines not widely available in India. The medication is delivered directly to the hospital where the patient is undergoing treatment.

I want to buy Orladeyo in Hyderabad. How can I access it?

To access Orladeyo in Hyderabad, patients should first consult their oncologist. Once prescribed, the medicine can be arranged through authorized channels under NPP guidelines and delivered to the treating hospital, such as Basavatarakam Indo-American Cancer Hospital.

I want to buy Orladeyo in Bangalore. How can I access it?

Patients seeking access to Orladeyo in Bangalore should consult their oncologist for evaluation and prescription. Following this, the medicine can be procured through compliant import channels and delivered to the treating hospital, such as HCG Cancer Center and Fortis Hospital, Bangalore.

Can I buy Orladeyo at major hospitals like AIIMS, Medanta, Apollo, or Fortis?

Orladeyo can be accessed at leading hospitals such as AIIMS Delhi, Medanta – The Medicity, Apollo Hospitals Chennai, Fortis Memorial Research Institute, Kokilaben Dhirubhai Ambani Hospital, P. D. Hinduja Hospital, Manipal Hospitals, Aster Medcity, Indraprastha Apollo Hospital, King George’s Medical University (KGMU), Shalby Hospitals, Tata Memorial Centre, HCG Cancer, Basavatarakam Indo-American Cancer Hospital, Cancer Institute (WIA), Max Healthcare, and Rajiv Gandhi Cancer Institute & Research Centre through the Named Patient Program (NPP) with a valid oncologist’s prescription. Indian Pharma Network assists with import and delivery to the treating hospital.

How does Orladeyo Import in India work?

Orladeyo Import in India is possible through the Named Patient Program. This means the medicine can be imported for a specific patient with a valid doctor’s prescription. Indian Pharma Network helps manage the complete process, including approvals and delivery, making sure the medicine reaches the patient safely and legally.

Who is a reliable Orladeyo supplier in India?

Indian Pharma Network is a trusted Orladeyo supplier in India, facilitating compliant access through global sourcing channels and structured documentation support for eligible patients under applicable regulatory provisions.

How much does Orladeyo cost in India?

Orladeyo is not yet approved in India. However, patients in India can legally access it through the provision called the Named Patient Program (NPP). Orladeyo prices may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Orladeyo cost in India, please call/WhatsApp +91 98104 69557 or send an email to info@indianpharmanetwork.in.

Can Orladeyo be available in SAARC countries?

Apart from Gulf countries, Orladeyo can be accessed through import provisions like the Named Patient Program (NPP) in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Orladeyo in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Orladeyo online in India?

Yes, one can buy Orladeyo in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not yet registered or available in their country. We can help facilitate the supply of Orladeyo through legal channels.

Where can Orladeyo be shipped in India?

We can assist patients and healthcare providers in accessing Orladeyo across major cities and states in India through the Named Patient Program (NPP).

We can ship Orladeyo in Ahmedabad, Amritsar, Aurangabad, Bangalore, Bhopal, Bhubaneswar, Chandigarh, Chennai, Coimbatore, Dehradun, Delhi, Faridabad, Ghaziabad, Goa, Gurgaon, Guwahati, Hyderabad, Indore, Jaipur, Jammu Kashmir, Kanpur, Kochi, Kolkata, Lucknow, Ludhiana, Madurai, Mangalore, Mumbai, Mysore, Nagpur, Nashik, Navi Mumbai, Noida, Patna, Pune, Raipur, Ranchi, Surat, Thane, Trivandrum, Vadodara, Varanasi, Vijayawada, Visakhapatnam, and other cities across India.

Who is an authorized Orladeyo importer in India?

Indian Pharma Network acts as the Orladeyo importer in India, assisting with Named Patient Import processes, regulatory documentation, and compliant international procurement for patients requiring this therapy.

In which countries is Orladeyo approved?

Orladeyo (berotralstat) has been approved in over 30 countries globally, including the U.S., Canada, Japan, the U.K., the UAE, Saudi Arabia, and the European Union. It is also approved across much of Latin America, including Brazil, Mexico, Argentina, Chile, Colombia, and Peru, for the prevention of hereditary angioedema (HAE) attacks.

Can I buy Orladeyo from Europe, the USA, or other countries?

As of now, Orladeyo is approved and available in the U.S., Canada, Japan, the U.K., the UAE, Saudi Arabia, Brazil, Mexico, Argentina, Chile, Colombia, and the European Union, but patients in India cannot directly purchase it from abroad. It can be legally accessed through the Named Patient Program (NPP) with a valid prescription. Indian Pharma Network assists with compliant sourcing and delivery to the treating hospital.

What are the storage conditions of Orladeyo® Capsules?

Store the oral capsules at 20ºC to 25ºC (68ºF to 77ºF). Excursions permitted between 15ºC and 30ºC (59ºF to 86ºF).