Temozolomide for Injection

Temozolomide for injection is indicated for the treatment of adult patients with newly diagnosed glioblastoma multiforme, concomitantly with radiotherapy and then as maintenance treatment, and for adult patients with refractory anaplastic astrocytoma.

Temozolomide is an alkylating agent that, once it converts to its active form, methylates DNA at specific sites, damaging the DNA of rapidly dividing tumor cells and triggering cell death — the injectable form is used when oral administration is not feasible.

• Myelosuppression, including severe neutropenia and thrombocytopenia, is a significant risk; regular blood count monitoring is required.
• Hepatotoxicity has been reported, including rare cases of severe liver injury; liver function tests should be monitored.
• Pneumocystis jirovecii pneumonia (PJP) prophylaxis may be required, especially during the concomitant phase with radiotherapy.
• Secondary malignancies, including myelodysplastic syndrome, have been reported with long-term use.

What documents are required to import Temozolomide Injection to India?

Temozolomide injection may be imported in the patient’s name only, by patients or government hospitals. The following documentation is required:

• A valid prescription from a registered neuro-oncologist
• Diagnostic/pathology report confirming glioblastoma or anaplastic astrocytoma diagnosis
• Patient ID proof (issued by the Government of India)

How is the order confirmed?

The order is confirmed only after receipt and verification of a valid prescription.

Is Temozolomide Injection available in India?

This specific injectable formulation is not commercially marketed in India. It can be legally accessed through the Named Patient Program (NPP).

Indian Pharma Network (IPN) can source Temozolomide for injection from its authorized distribution network and facilitate supply to patients, doctors, and hospitals under applicable legal provisions.

For cost in India and availability, contact IPN at Phone: +91-9310090915 or email info@indianpharmanetwork.in.

Global Approval Status:

• United States: Approved by the FDA (injectable formulation of temozolomide).

What is Temozolomide Injection used for?

It treats newly diagnosed glioblastoma multiforme (with radiotherapy) and refractory anaplastic astrocytoma.

Who manufactures Temozolomide Injection?

Multiple manufacturers produce temozolomide for injection; the originator oral form is Merck’s Temodar.

How is it administered?

By intravenous infusion, typically over 90 minutes, on a schedule set by the treating oncologist.

How much does it cost in India?

Cost depends on treatment cycles and sourcing logistics — share your prescription with IPN for a quote.