Exparel (Bupivacaine Liposome)
- Medicine Name: Exparel
- API: Bupivacaine Liposome
- Dosage Form & Strength: Injectable suspension: 266 mg/20 mL (13.3 mg/mL) & 133 mg/10 mL (13.3 mg/mL) single-dose vial
- Manufactured By: Pacira Pharmaceuticals, Inc.
Exparel (bupivacaine liposome injectable suspension) is used:
In patients aged 6 years and older for single-dose infiltration to produce postsurgical local analgesia.
In adults as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia.
Local Analgesia via Infiltration Dosing in Adults: The recommended dose for local infiltration in adults is up to a maximum dose of 266 mg (20 mL), and is based on the size of the surgical site, volume required to cover the area, and individual patient factors that may impact the safety of an amide local anesthetic.
Local Analgesia via Infiltration Dosing in Pediatric Patients: The recommended dose for single-dose infiltration in pediatric patients, aged 6 to less than 17 years, is 4 mg/kg (up to a maximum of 266 mg), and is based upon two studies of pediatric patients undergoing either spine surgery or cardiac surgery.
Regional Analgesia via Interscalene Brachial Plexus Nerve Block Dosing in Adults: The recommended dose for interscalene brachial plexus nerve block in adults is 133 mg (10 mL), and is based upon one study of patients undergoing either total shoulder arthroplasty or rotator cuff repair.
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