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Leukine (Sargramostim)

  • Medicine Name: Leukine
  • API: Sargramostim
  • Dosage Form & Strength: For injection (lyophilized powder): 250 mcg of sargramostim in a single-dose vial for reconstitution
  • Manufactured By: Partner Therapeutics, Inc.

Medical Uses

Leukine (sargramostim) is a leukocyte growth factor used:

  • To shorten the time to neutrophil recovery and to reduce the incidence of severe and life-threatening infections and infections resulting in death after induction chemotherapy in adult patients aged 55 years and older with acute myeloid leukemia (AML).
  • For the mobilization of hematopoietic progenitor cells into peripheral blood for collection by leukapheresis and autologous transplantation in adult patients.
  • For the acceleration of myeloid reconstitution after autologous bone marrow or peripheral blood progenitor cell transplantation in adult and pediatric patients aged 2 years and older.
  • For the acceleration of myeloid reconstitution after allogeneic bone marrow transplantation in adult and pediatric patients aged 2 years and older.
  • For the treatment of delayed neutrophil recovery or graft failure after autologous or allogeneic bone marrow transplantation in adult and pediatric patients aged 2 years and older.
  • To increase survival in adult and pediatric patients from birth to 17 years of age acutely exposed to myelosuppressive doses of radiation (Hematopoietic Syndrome of Acute Radiation Syndrome [H-ARS]).

Recommended Dosage:
The recommended dosage of Leukine generally depends on the specific indication and clinical status of the patient. It may be injected either subcutaneously or intravenously, typically once daily, after chemotherapy or a bone marrow transplant. Doctors watch white blood cell numbers and any side effects to decide if the dose needs to be changed. Start administration at an appropriate time after treatment, as guided by clinical protocols. Always use it under the proper supervision of a qualified healthcare provider (HCP) familiar with hematopoietic recovery therapies. Regular monitoring of blood counts and patient condition is important to ensure safe and effective use.

Warning & Precautions

  • Treatment with Sargramostim may cause serious allergic reactions, including breathing difficulty, rash, or swelling. Patients with yeast allergies must be cautious. Stop treatment promptly in case signs of hypersensitivity occur, and consult a healthcare provider (HCP) for emergency medical help.
  • This infusion can cause chills, fever, low blood pressure, or shortness of breath. Monitor closely during and after infusion. Reactions usually arise within hours, and pre-medication or slower infusion may help minimize risks.
  • Do not give this infusion within 24 hours before or after chemotherapy or radiotherapy. Doing so may be responsible for worsening bone marrow suppression, causing very low blood counts. Proper timing is important to avoid serious complications such as infections or bleeding.
  • Sargramostim 250 mcg injection can cause fluid accumulation in the lungs or around the heart, or cause capillary leak syndrome—a rare but life-threatening condition causing low blood pressure, swelling, and organ problems. Discontinue use if these signs and symptoms develop and seek immediate care.
  • Some patients may experience abnormal heart rhythms, especially those with existing heart conditions. Symptoms like palpitations or dizziness should be reported. Monitor heart function during therapy if the patient has a history of cardiac issues or shows new symptoms.
  • This medicine may cause a very high white blood cell count, which can be responsible for blood thickening or clotting. Regular blood tests are required. If counts get excessive, dose adjustment or stopping treatment may be required.
  • Therapy with Sargramostim injection might stimulate certain unhealthy cells, mainly in leukemia or myelodysplasia. Use with proper caution in those with these cancers. Monitor disease progression precisely during treatment and consult healthcare specialists when necessary.
  • This medicine should be used during pregnancy only when necessary. It may be responsible for affecting fetal development. Pregnant women should consult their healthcare provider (HCP) and weigh the risks versus the benefits before initiating treatment.
  • It is not known if this medicine passes into human breast milk. Breastfeeding is not required while on this treatment, as it may pose risks to the nursing baby. Discuss existing alternatives with your healthcare provider (HCP)

Documentation & Availability

What documents are required to import LEUKINE to India?

LEUKINE (sargramostim) injections can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

  • A valid prescription from a qualified doctor.
  • Patients diagnostic reports
  • Patient ID proof (issued by the government of India)
How does the order get confirmed?

The order will be confirmed only after the receipt of:

  • A valid prescription from the Doctor
  • Import permit if applicable
Is LEUKINE available in India?

LEUKINE (sargramostim injections) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

  • On availability of Leukine in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
  • On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait,
  • Iraq, Saudi Arabia, and the UAE).
  • Medicine Price.
  • Finding Genuine and reliable sources from the USA, Canada,
  • Europe, and Australia
  • Ensuring 100% transparency.

LEUKINE can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of LEUKINE (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Leukine 250 mcg injection price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Sourcing & Delivery

Indian Pharma Network can source LEUKINE (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

FAQ

What is the Generic Name for the trade name drug Leukine®?

Sargramostim is the Generic Name for the trade name drug Leukine®.

What is the Manufacturer's Name of Leukine®?

Leukine® is manufactured by Partner Therapeutics, Inc.

Is Leukine® approved by the FDA?

Yes, Leukine® is approved by the FDA. Date of first approval: March 1991.

What is the dosage and form of Leukine® supplied?

Leukine is supplied for injection: 4 mg or 20 mg of Sargramostim as a lyophilized powder in a single-dose vial for reconstitution for intravenous (IV) use.

What are the most common side effects of Leukine® 250 mcg injection?

The most common side effects of Leukine® are swelling, breathing problems, stomach pain, nausea, vomiting, diarrhea, loss of appetite, weight loss, urination problems, fever, weakness, not feeling well, mouth sores, headache, high blood pressure, numbness, tingling, rash, itching; hair loss, and abnormal blood tests.

How much does Leukine® 250 mcg injection cost in India?

Prices of Leukine injections may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Leukine 250 mcg cost in India, please call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Leukine® 250 mcg injections be available in SAARC countries?

Apart from Gulf countries, Leukine® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Leukine® injection in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Leukine® 250 mcg injection online in India?

Yes, one can buy Leukine 250 mcg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the legal supply of Leukine® injection through legal channels.

What are the storage conditions of Leukine® 250 mcg injections?

Store vials refrigerated at 2 to 8°C (36 to 46°F) in the original carton to protect from light. Do not freeze or shake the vials. Do not use after the expiration date printed on the vial.

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