Ofev (Nintedanib)

Ofev (Nintedanib) is a kinase inhibitor used in adults for:

• Treatment of idiopathic pulmonary fibrosis (IPF).
• Treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype.
• Slowing the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD)

  Recommended Dosage:
  The recommended dosage of Nintedanib is 150 mg taken orally twice daily, administered approximately 12 hours apart. Nintedanib capsules should be taken with food and swallowed whole with liquid. The capsules should not be chewed because of the bitter taste. Capsules should not be opened or crushed.If contact with the content of the capsule occurs, wash hands immediately and thoroughly. The effect of chewing or crushing the capsule on the pharmacokinetics of nintedanib is not known.

If a dose of Nintedanib is missed, the next dose should be taken at the next scheduled time. Advise the patient not to make up for a missed dose. Do not exceed the recommended maximum daily dosage of 300 mg.

• Do not use this therapeutic drug in those with moderate or serious hepatic impairment. Patients with liver dysfunction may experience increased exposure to the medicine. This may lead to a higher risk of side effects. Liver function must be monitored before and throughout treatment.
• Treatment with this medicine can cause elevations in ALT, AST, or bilirubin, which may indicate liver injury. Monitor liver enzymes often. Temporarily halt, reduce dose, or discontinue treatment if significant liver abnormalities occur. Educate patients to report signs and symptoms of jaundice or dark-colored urine promptly.
• Vomiting, diarrhea, and nausea are common with Nintedanib 150 mg/100 mg and may need supportive care or dose modification. Persistent symptoms can cause dehydration and electrolyte imbalance. Patients need to maintain hydration and inform healthcare providers (HCPs) in case symptoms are serious or persistent.
• Treatment with Nintedanib may cause harm to the developing fetus. It is contraindicated during pregnancy. Females of reproductive age should use effective contraception during treatment and for at least 90 days after the final dose. Confirm pregnancy status before initiating this therapy.
• Serious arterial events, including myocardial infarction, may occur with Nintedanib treatment. Patients with a history of cardiovascular risk factors require close monitoring. Stop treatment if signs of thromboembolism develop. Patients should report shortness of breath, chest pain, or stroke symptoms promptly.
• This medicine increases the risk of bleeding, particularly in those taking anticoagulants. Use it with caution in those with past bleeding disorders or on medicines that affect coagulation. Monitor closely for signs and symptoms of bleeding and adjust treatment accordingly if any serious bleeding occurs.
• Cases of gastrointestinal perforation, some fatal, may occur. Use this medicine with caution in patients with a known history of abdominal surgery or gastrointestinal conditions that may increase the risk. Quickly evaluate any symptoms like serious abdominal pain, and stop therapy if perforation is suspected.
• Significant proteinuria, including nephrotic syndrome, may occur with the use of Nintedanib. Monitor urine protein levels and renal function periodically. Stop treatment in case patients develop nephrotic-range proteinuria or significant renal impairment, and refer to a nephrologist for further evaluation and management.

What documents are required to import OFEV to India?

OFEV (nintedanib) capsules can be imported by patients or government hospitals in the name of the patients only.
The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
• Patients diagnostic reports
• Patient ID proof (issued by the government of India)

How does the order get confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
• Import permit if applicable

Is OFEV available in India?

Ofev (nintedanib capsules) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator, providing input

• On availability of Ofev in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait,
• Iraq, Saudi Arabia, and the UAE).
• Medicine Price.
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
• Ensuring 100% transparency.

OFEV can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune, and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of OFEV (prescription medicines) to all locations in the world and India after fulfilling the legal requirements (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Ofev 150 mg/100 mg Capsule price in India.

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source OFEV (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient's address only from New Delhi, India.

What is the Generic Name for the trade name drug Ofev®?

Nintedanib is the Generic Name for the trade name drug Ofev®.

What is the Manufacturer's Name of Ofev®?

Ofev® is manufactured by Boehringer Ingelheim Pharmaceuticals, Inc.

Is Ofev® approved by the FDA?

Yes, Ofev® is approved by the FDA. Date of first approval: October 15, 2014.

What is the dosage and form of Ofev® supplied?

Ofev is supplied in capsules: 150 mg and 100 mg for oral administration.

What are the most common side effects of Ofev® 150 mg/100 mg Capsule?

The most common side effects of Ofev® are diarrhea, decreased weight, liver enzyme elevation, vomiting, nausea, abdominal pain, decreased appetite, headache, and hypertension.

How much does Ofev® 150 mg/100 mg Capsule cost in India?

Prices of Ofev capsules may fluctuate over time because of market dynamics and regulatory changes. For the most transparent and latest Ofev 150 mg/100 mg cost in India, please call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Ofev® 150 mg/100 mg Capsules be available in SAARC countries?

Apart from Gulf countries, Ofev® can be available in SAARC countries (India, Afghanistan, Maldives, Nepal, Bangladesh, Bhutan, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the legal supply of Ofev® Capsule in these countries. We help provide legal access to this therapeutic drug through our reliable channels.

Is it safe to buy Ofev® 150 mg/100 mg Capsule online in India?

Yes, one can buy Ofev 150 mg/100 mg online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the legal supply of Ofev® Capsule through legal channels.

What are the storage conditions of Ofev® 150 mg/100 mg Capsules?

Store at 20 to 25°C (68 to 77°F); excursions permitted to 15 to 30°C (59 to 86°F). Protect from exposure to high humidity and avoid excessive heat. If repackaged, use a USP tight container.