Lamzede (Velmanase alfa-tycv)
- Medicine Name: Lamzede
- API: Velmanase alfa-tycv
- Dosage Form & Strength: Injection: 10 mg as a lyophilized powder in a single-dose vial for reconstitution
- Manufactured By: Chiesi Global Rare Diseases
Lamzede (velmanase alfa-tycv) is the first and only enzyme replacement therapy (ERT) used for the treatment of non-central nervous system manifestations of alpha-mannosidosis in adult and pediatric patients.
Recommended Dosage: The recommended dosage is 1 mg/kg (actual body weight) given once weekly as an intravenous (IV) infusion. The total volume of infusion is specified by the patient’s actual body weight and needs to be given over at least 60 minutes for those weighing up to 49 kg. Those weighing 50 kg and beyond need to be infused at the highest infusion rate of 25 mL/hour to manage the protein load.
In case single or multiple doses are missed, reinitiate the therapy as quickly as possible, as long as it is at least three days from the very next scheduled dose. In case it is within 3 days from the next scheduled dose, give only the next dose per schedule.
- Hypersensitivity reactions including anaphylaxis may occur in those treated with Lamzede. Apt medical support must readily exist when velmanase alfa is used. In case of serious allergic or anaphylactic-type reactions, promptly discontinue velmanase alfa and follow current medical standards for emergency treatment.
- Use of velmanase alfa may result in an infusion-related reaction (IRR), including an anaphylactoid reaction. The IRRs noticed in clinical trials of velmanase alfa were characterized by a rapid onset of signs and symptoms and were of mild-moderate severity. The patient must be kept under regular observation for IRRs for 60 minutes or longer after the infusion, as per the treating clinician’s judgment.
- Antibodies may play a significant role in treatment-related reactions that occurred with the use of Lamzede. To further assess the relationship, in instances of the establishment of critical IRRs or lack or loss of therapy effect, patients need to be tested for the existence of anti-velmanase alfa antibodies. If the patient’s condition deteriorates throughout ERT, cessation of therapy must be considered.
- As Lamzede injections aims at normalizing alpha-mannosidase in alpha-mannosidosis patients, this drug is not recommended during pregnancy unless the clinical condition of the respective candidates requires velmanase alfa treatment.
- It is not known whether this medicine or its metabolites are excreted in milk. Nevertheless, the absorption of any ingested milk-containing velmanase alfa in the breastfed baby is considered to be mild and no unwanted effects are therefore anticipated. Lamzede injection can be used by nursing mothers.
What documents are required to import LAMZEDE to India?
LAMZEDE (velmanase alfa-tycv) for injection can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patients ID proof (issued by the government of India)
How does the order be confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from Doctor
- Import permit if applicable
Is LAMZEDE available in India?
LAMZEDE (velmanase alfa-tycv injections) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input
- On availability of Lamzede in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
- Medicine price
- Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
- Ensuring 100% transparency
LAMZEDE can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Gao, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.
IPN (Indian Pharma Network) can facilitate the supply of LAMZEDE (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).
Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Lamzede 10 mg price in India.
We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
What is the Generic Name for the trade name drug Lamzede®?
Velmanase alfa-tycv is a Generic Name for the trade name drug Lamzede®.
What is the Manufacturer’s Name of Lamzede®?
Lamzede® is manufactured by Chiesi Global Rare Diseases.
Is Lamzede® approved by the FDA?
Yes, Lamzede® is approved by the FDA. Date of approval: February 16, 2023.
Where can I get Lamzede® at the best price in India?
To get the best Lamzede price in India, kindly contact the Indian Pharma Network (a WHO GDP and ISO 9001:2008 certified company). For Lamzede®, a valid medical prescription is required from a treating physician.
What is the dosage and form of Lamzede® supplied?
Lamzede® is supplied as injections: 10 mg of velmanase alfa-tycv as a lyophilized powder in a single-dose vial for reconstitution for intravenous administration.
What are the most common side effects of Lamzede®?
The most common side effects of Lamzede® are hypersensitivity reactions including anaphylaxis, pyrexia, nasopharyngitis, headache, and arthralgia.
How much does Lamzede® cost in India?
The cost of Lamzede in India can vary. In order to procure this enzyme replacement therapy (ERT) legally, you can Call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.
What are the storage conditions of Lamzede®?
Store the vials refrigerated at 2-8°C (36-46°F) in the original carton to protect them from the light. Never freeze the vials.
Is it safe to buy Lamzede®online in India?
Yes, one can buy Lamzede online in India at the lowest price from the Indian Pharma Network (IPN) if it is not (yet) registered or available in their country. We can help facilitate the supply of Lamzede® through legal channels.
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