Lupkynis (Voclosporin)
- Medicine Name: Lupkynis
- Generic Name: Voclosporin
- Dosage Form & Strength: Capsules: 7.9 mg
- Manufactured By: Aurinia Pharmaceuticals Inc.
Lupkynis is a calcineurin-inhibitor immunosuppressant used in combination with a background immunosuppressive therapy regimen for the treatment of adult patients with active lupus nephritis (LN).
Recommended Dosage: The recommended starting dose is 23.7 mg twice daily. Use lupkynis capsules together with mycophenolate mofetil (MMF) and corticosteroids. Capsules must be swallowed completely and must not be crushed, opened, or divided. Take it on an empty stomach persistently as close to a 12-hour schedule as possible, and with a minimum of 8 hours between doses.
If a dose is missed, the patient should take it as soon as possible within 4 hours after missing the dose. Beyond the 4-hour time frame, patients should wait until the usual scheduled time to take the next regular lupkynis dose. Patients should not double the next dose of lupkynis.
- Patients should be evaluated for skin changes and advised to avoid or limit sun exposure and to avoid artificial UV light (sun lamps, tanning beds) by wearing protective clothing and using a broad spectrum sunscreen (SPF 30 or higher).
- Immunosuppressants, including Lupkynis 7.9 mg capsules, increase the risk of having bacterial, fungal, viral, and protozoal infections, including opportunistic infections. Monitor for infection. Consider the benefits/risks for patients; use the lowest effective dosage required to maintain response.
- Voclosporin, like other calcineurin-inhibitors, can cause acute or chronic nephrotoxicity. Evaluate eGFR on a regular interval during treatment, and consider dose reduction or interruption in patients with reductions in eGFR; persistent decrease of eGFR needs to be assessed for chronic calcineurin-inhibitor nephrotoxicity.
- Hypertension is a common side effect due to the therapy with lupkynis 7.9 mg capsule and may require antihypertensive therapy. Monitor blood pressure on a regular basis during therapy and treat new-onset hypertension and exacerbations of pre-existing hypertension.
- Voclosporin, like other calcineurin-inhibitors, may be responsible for causing a spectrum of neurotoxicities. Assess for neurologic symptoms and consider dose reduction or interruption of Voclosporin therapy in case neurotoxicity occurs.
- Hyperkalemia, which may be severe and require treatment, has been observed with calcineurin-inhibitors including therapy with Lupkynis 7.9 mg Capsules. Assess serum potassium levels periodically during therapy.
- Avoid the use of live attenuated vaccines during treatment with Voclosporin (e.g., BCG, intranasal influenza, mumps, measles, rubella, oral polio, varicella, yellow fever, and TY21a typhoid vaccines). Inactivated vaccines observed to be safe for administration may not be sufficiently immunogenic during therapy with Voclosporin.
- Female patients of the potential risk to a fetus should avoid use of Voclosporin during pregnancy. Females should inform their health specialist if they are pregnant or become pregnant. Women should not breastfeed during treatment with Voclosporin and for 7 days after the last dose of Voclosporin.
What documents are required to import LUPKYNIS to India?
LUPKYNIS (voclosporin) capsules can be imported by patients or government hospitals on the name of the patients only.
The following documentation required to import the product:
- Valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patients id proof (issued by government of India)
How does order be confirmed?
The order will be confirmed only after the receipt of:
- Valid prescription of Doctor
- Import permit if applicable
Is LUPKYNIS available in India?
LUPKYNIS (voclosporin capsules) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is facilitator providing input
- On availability of Lupkynis 7.9 mg capsules in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
- Medicine Price.
- Finding Genuine and reliable source from Canada, Europe, USA and Australia
- Ensuring 100% transparency.
LUPKYNIS can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.
IPN (Indian Pharma Network) can facilitate the supply of LUPKYNIS (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable)
Please contact +91-9310090915 | Toll-Free No: 1800-889-1064 or write us at info@indianpharmanetwork.in for Voclosporin price in India.
We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.
Indian Pharma Network is able to source the LUPKYNIS (Cancer Treatment Medicines) from across the globe, and has the ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.
Indian Pharma Network is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Lupkynis®?
Voclosporin is Generic Name for the trade name drug Lupkynis®.
What is the Manufacturer Name of Lupkynis®?
Lupkynis (Voclosporin Capsules) is manufactured by Aurinia Pharmaceuticals Inc.
Is Lupkynis® approved by the FDA?
Yes, Lupkynis® is approved by the FDA. Date of approval: January 22, 2021.
Is Lupkynis a steroid?
No, it is not a steroid/corticosteroid medication. It’s a medicine named a calcineurin-inhibitor. Sometimes calcineurin inhibitors and corticosteroids are used together for treating lupus nephritis.
What is the cause of lupus nephritis?
Lupus nephritis is a kidney disease caused by systemic lupus erythematosus link (SLE or lupus). Lupus is an autoimmune disease link; a disorder in which the body’s defense system attacks the body’s own cells and organs. Kidney disease caused by lupus may get worse as time progresses and may lead to kidney failure.
What are the most common side effects due to Lupkynis®?
Most common side effects due to Lupkynis® include: acute kidney injury, hypertension, diarrhea, abdominal pain, headache, anemia, cough, urinary tract infection, abdominal pain upper, dyspepsia, renal impairment, alopecia, mouth ulceration, decreased appetite, fatigue, and tremor.
How much does Lupkynis® cost in India?
Lupkynis cost in India is very reasonable. To procure this lupus nephritis medication authentically, you can call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.
What are the storage conditions of Lupkynis®?
Store at 20 to 25°C (68 to 77°F); excursions permitted to 15 to 30°C (59 to 86°F). Do not put this drug in another container. Keep it in their original packaging until ready to be taken.
Is it safe to buy Lupkynis Capsules online in India?
Yes, In order to buy Lupkynis 7.9 mg capsules online in India, always go with an absolutely legitimate, WHO-GDP & ISO certified Pharmaceutical Wholesaler/Distributor/Supplier.
What are the Highlights of prescribing information for Lupkynis®?
Click Here to download full Lupkynis prescribing information.
Contact Patient Support
If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.
Disclaimer
CMV retinitis is kind of an eye infection caused by a virus. CMV mainly attacks the retina of the eye and can be responsible for causing loss of vision, and eventually may lead to the blindness. Patients with acquired immunodeficiency syndrome are more likely to develop CMV retinitis. CMV retinitis is kind of an eye infection caused by a virus. CMV mainly attacks the retina of the eye and can be responsible for causing loss of vision, and eventually may lead to the blindness. Patients with acquired immunodeficiency syndrome are more likely to develop CMV retinitis.