Pyrukynd (Mitapivat)
Pyrukynd (Mitapivat)
- Medicine Name: Pyrukynd
- Generic Name: Mitapivat
- Dosage Form & Strength: Tablets: 5 mg, 20 mg, and 50 mg
- Manufactured By: Agios Pharmaceuticals, Inc.
Pyrukynd (mitapivat) is a pyruvate kinase activator used for the treatment of reduced red blood cell counts caused by the early breakdown of red blood cells (hemolytic anemia) in adult patients with PK (also called pyruvate kinase) deficiency.
Recommended Dosage: The starting recommended dosage for Pyrukynd tablet is 5 mg orally twice daily with or without food. Swallow tablets whole. Do not chew, crush, split, or dissolve. To gradually increase hemoglobin (Hb), titrate the dosage of Pyrukynd from 5 mg twice daily to 20 mg twice daily, and then to the maximum dose of 50 mg twice daily, with these dose increases occurring every four weeks. Evaluate Hb and transfusion need prior to increasing to the very next dose level, as certain individuals may reach and maintain normal Hb at 5 mg twice daily or 20 mg twice daily. Discontinue therapy in case no benefit has been noticed by 24 weeks, on behalf of hemoglobin and hemolysis laboratory results and transfusion needs.
If a dose is missed by 4 hours or less, administer the dose as quickly as possible. In case a dose is missed beyond four hours, avoid administering a replacement dose, and wait until the very next scheduled dose. Subsequently, back to the standard dosing schedule.
- Acute hemolysis with subsequent anemia may occur after abrupt interruption or discontinuation of Pyrukynd 5 mg, 20 mg, and 50 mg tablets in a dose-ranging study. Do not abruptly discontinue treatment. Gradually taper the dose to discontinue therapy if possible.
- When discontinuing treatment with Pyrukynd, monitor patients for signs of acute hemolysis and anemia including dark urine, jaundice, scleral icterus, dizziness, fatigue, confusion, or shortness of breath.
- Untreated pyruvate kinase deficiency in pregnant females may precipitate pre-term labor, acute hemolysis, miscarriage, and severe/critical anemia requiring frequent transfusion. Additionally, preeclampsia and serious hypertension have been noticed.
- Pyrukynd undergoes extensive hepatic metabolism. Moderate and serious hepatic impairment is expected to elevate the systemic exposure of mitapivat. Avoid the use of this medicine in those with moderate and critical hepatic impairment.
What documents are required to import PYRUKYND to India?
PYRUKYND (mitapivat) tablets can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patients diagnostic reports
- Patients ID proof (issued by the government of India)
How does the order be confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from Doctor
- Import permit if applicable
Is PYRUKYND available in India?
PYRUKYND (mitapivat tablets) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input
On availability of Pyrukynd in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
- Medicine Price.
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PYRUKYND can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.
IPN (Indian Pharma Network) can facilitate the supply of PYRUKYND (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).
Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Pyrukynd 5 mg/20 mg/50 mg price in India.
We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Indian Pharma Network is able to source the PYRUKYND (Cancer Treatment Medicines) from across the globe and has the ability to supply. Indian Pharma offers its customers worldwide access to the best available treatment.
Indian Pharma Network (IPN) is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
What is the Generic Name for the trade name drug Pyrukynd®?
Mitapivat is a Generic Name for the trade name drug Pyrukynd®.
What is the Manufacturer’s Name of Pyrukynd®?
Pyrukynd® is manufactured by Agios Pharmaceuticals, Inc.
Is Pyrukynd® approved by the FDA?
Yes, Pyrukynd® is approved by the FDA. Date of approval: February 17, 2022.
Where can I get Pyrukynd® at the best price in India?
To get the best Pyrukynd price in India, kindly connect with the Indian Pharma Network (a WHO GDP and ISO 9001:2008 certified company). For Pyrukynd®, a valid medical prescription is needed from a treating physician.
What is the dosage and form of Pyrukynd® supplied?
Pyrukynd® is supplied as Tablets: 5 mg, 20 mg, and 50 mg for oral administration.
What are the most common side effects of Pyrukynd®?
The most common side effects of Pyrukynd® are estrone decreased (males), back pain, increased urate, arthralgia, and estradiol decreased (males).
How much does Pyrukynd® cost in India?
The cost of Pyrukynd in India can vary. In order to procure this kinase activator legally, you can call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.
What are the storage conditions of Pyrukynd®?
Store at 20-25°C (68-77°F) with excursions permitted between 15°C and 30°C (59°F and 86°F). Store the blister wallets of Pyrukynd® in the original carton until the time of use.
Is it safe to buy Pyrukynd® online in India?
Yes, one can buy Pyrukynd online in India at the lowest price from the Indian Pharma Network (IPN) if the medicine Pyrukynd® is not (yet) registered or available in their country. We can help facilitate the supply of Pyrukynd® through legal channels.
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