Sohonos (Palovarotene)

Sohonos (palovarotene) is a retinoid used for reduction in the volume of new heterotopic ossification in adults and children aged 8 years and older for females and 10 years and older for males with fibrodysplasia ossificans progressiva (FOP).

Recommended Dosage: 
Recommended Dosage for Adults and Pediatric Patients Aged 14 Years and Older: 

• Daily Dose: The recommended daily dosage for adults and pediatric patients 14 years and older is 5 mg daily. Discontinue daily dosing when flare-up dosing starts.
  
• Flare-up Dose: The recommended flare-up dosage for adults and pediatric patients 14 years and older is 20 mg daily for 4 weeks, followed by 10 mg daily for 8 weeks (for a total of 12 weeks of flare-up therapy), even if symptoms resolve earlier, then return to daily dosing of 5 mg.  

Recommended Dosage for Pediatric Patients Aged 8-13 Years for Females and Aged 10-13 Years for Males:

• Daily Dose: The recommended daily dosage for patients under 14 years of age is weight-based ranging from 2.5 mg to 5 mg daily. Discontinue daily dosing when flare-up dosing starts.
  
• Flare-up Dose: The recommended flare-up dosage for patients under 14 years of age is weight based. 
  

• Sohonos treatment can cause fetal harm and should not be used during pregnancy. Females of reproductive age should use an effective method of contraception at least one month prior to therapy, during treatment with Sohonos capsules, and for 1 month after the final dose.
  
• Patients should not donate blood during therapy with Palovarotene and for 1 week following discontinuation because the blood might be administered to a pregnant patient whose fetus must not be exposed to palovarotene. 
  
• Palovarotene can cause irreversible premature epiphyseal closure and potential side effects on growth. Monitoring of linear growth is required in growing pediatric patients. Prior to starting therapy, all growing pediatric patients should undergo baseline assessment of skeletal maturity via hand/wrist and knee x-rays, standard growth curves, and pubertal staging.
  
• New or worsening psychiatric events may occur with the use of Palovarotene. These include anxiety, depression, mood alterations, and suicidal thoughts and behaviors. Monitor patients for the development of new or worsening psychiatric symptoms during therapy with Palovarotene.
  

What documents are required to import SOHONOS to India?

SOHONOS (palovarotene) capsules can be imported by patients or government hospitals on the name of the patients only. 

The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
  
• Patients diagnostic reports
  
• Patients ID proof (issued by the government of India)
  

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from Doctor
  
• Import permit if applicable

SOHONOS (palovarotene capsules) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input

• On availability of Sohonos in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
  
• Medicine Price.
  
• Finding Genuine and reliable sources from the USA, Canada, Europe, and Australia
  
• Ensuring 100% transparency.

IPN (Indian Pharma Network) can facilitate the supply of SOHONOS (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Sohonos price in India. 

We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

What is the Generic Name for the trade name drug Sohonos®?

Palovarotene is a Generic Name for the trade name drug Sohonos®.

What is the Manufacturer’s Name of Sohonos®?

Sohonos® is manufactured by Ipsen Biopharmaceuticals, Inc.

Is Sohonos® approved by the FDA?

Yes, Sohonos® is approved by the FDA. Date of first approval: August 16, 2023.

What is the dosage and form of Sohonos® supplied?

Sohonos® is supplied as Capsules: 1 mg/1.5 mg/2.5 mg/5 mg/10 mg for oral administration. 

What are the most common side effects of Sohonos®? 

The most common side effects of Sohonos® are back pain, dry skin, arthralgia, pruritis, alopecia, fatigue, erythema, musculoskeletal pain, myalgia, headache, skin exfoliation, nausea, dry eye, hypersensitivity, peripheral edema, and rash.

How much does Sohonos® cost in India?

The cost of Sohonos in India can vary. To procure this retinoid legally, you can call or WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

What are the storage conditions of Sohonos®?

Store at 20-25°C (68-77°F); excursions permitted to 15-30°C (59-86°F). Capsules must be kept in the original carton to protect them from light.

Is it safe to buy Sohonos® online in India?

Yes, one can buy Sohonos online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the supply of Sohonos® through legal channels.