ZALTRAP (ziv-aflibercept)

 Zaltrap (ziv-aflibercept) is an FDA-approved anti-cancer medication given in combination with a chemotherapy regimen known as FOLFIRI for treating colorectal cancer that has spread. FOLFIRI combines the medications fluorouracil, leucovorin, and irinotecan. Zaltrap is an option for those who have had their cancer worsen or have become resistant to the initial therapy used for the treatment of their metastatic colorectal cancer (mCRC). Those who receive this drug have been previously treated with a chemotherapy named oxaliplatin.

Recommended Dosage: The recommended dosage of Zaltrap injection is 4 mg/kg of actual body weight administered as an intravenous (IV) infusion over 1 hour every two weeks in combination with FOLFIRI until there is evidence of disease progression or unacceptable toxicity. Administer the medicine before any component of the FOLFIRI regimen on the day of treatment.

• Treatment with Zaltrap 100 mg/4 mL or 200 mg/8 mL can increase the risk of severe bleeding. Patients should be monitored for signs of bleeding, such as unusual bruising, nosebleeds, or blood in stools. If severe hemorrhage occurs, Zaltrap treatment should be discontinued.
• This therapeutic drug may cause gastrointestinal perforations, which can be life-threatening. Symptoms like severe abdominal pain, fever, or changes in bowel habits should be reported immediately. If a perforation is confirmed, Zaltrap should be permanently discontinued. 
• Ziv-aflibercept can affect the body’s ability to heal wounds. Patients undergoing surgery should stop taking this medicine at least 4 weeks before the procedure and should not restart until the surgical wound is fully healed. 
• Ziv-aflibercept may cause high blood pressure. Blood pressure should be monitored regularly, and antihypertensive therapy may be needed to control it. Severe hypertension requires temporary or permanent discontinuation of the drug.
• Proteinuria (protein in the urine) is another potential side effect. Regular urine tests are recommended to detect this condition early. If proteinuria becomes severe, treatment with Zaltrap 200 mg/8 mL or 100 mg/4 mL should be temporarily stopped or discontinued.
• There is a risk of serious arterial thromboembolic events, including strokes and heart attacks. Patients with a history of these conditions should be closely monitored, and Ziv-aflibercept should be discontinued if severe events occur.
• Ziv-aflibercept can cause harm to a developing fetus. Women of childbearing potential should use effective contraception during treatment and for at least three months after the last dose. Pregnant women should be advised of the potential risks to the fetus.

What documents are required to import ZALTRAP to India?

ZALTRAP (ziv-aflibercept) injection can be imported by patients or government hospitals on the name of the patients only. 

The following documentation is required to import the product:

• A valid prescription from a qualified doctor.
  
• Patients diagnostic reports
  
• Patient ID proof (issued by the government of India)

How does the order be confirmed?

The order will be confirmed only after the receipt of:

• A valid prescription from the Doctor
  
• Import permit if applicable

Is ZALTRAP available in India?

ZALTRAP (ziv-aflibercept injection) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.

IPN (Indian Pharma Network) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input:

• On availability of Zaltrap in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune etc.)
  
• On availability in Gulf countries (Bahrain, Oman, Qatar, Kuwait, Iraq, Saudi Arabia, and the UAE).
  
• Medicine Price.
  
• Finding Genuine and reliable sources from the USA, Germany, Brazil, Canada, Europe, and Australia
  
• Ensuring 100% transparency.

ZALTRAP can be made available to patients, doctors, and hospitals in Mumbai, Goa, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.

IPN (Indian Pharma Network) can facilitate the supply of ZALTRAP (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable).

Please contact +91-9310090915 | Toll-Free Number: 1800-889-1064 or write us at info@indianpharmanetwork.in for Zaltrap injection price in India. 

We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.

Indian Pharma Network can source the ZALTRAP (Cancer Treatment Medicines) from across the globe and can supply. Indian Pharma offers its customers worldwide access to the best available treatment.

Indian Pharma Network (IPN) can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.

What is the Generic Name for the trade name drug Zaltrap®?

Ziv-aflibercept is a Generic Name for the trade name drug Zaltrap®.

What is the Manufacturer’s Name of Zaltrap®?

Zaltrap® is manufactured by Sanofi-aventis U.S. LLC.

Is Zaltrap® approved by the FDA?

Yes, Zaltrap® is approved by the FDA. Date of first approval: August 3, 2012.

What is the dosage and form of Zaltrap® supplied?

Zaltrap® is supplied as Injections: 100 mg/4 mL (25 mg/mL) and 200 mg/8 mL (25 mg/mL) solution in a single-dose vial for intravenous administration. 

What are the most common side effects of Zaltrap®? 

The most common side effects of Zaltrap® are leukopenia, diarrhea, proteinuria, AST increase, stomatitis, neutropenia, fatigue, thrombocytopenia, hypertension, weight decrease, decreased appetite, epistaxis, abdominal pain, serum creatinine increased, ALT increase, dysphonia, and headache.

How much does Zaltrap® cost in India?

Prices may fluctuate over time due to market dynamics and regulatory changes. To obtain accurate and up-to-date information on the cost of Zaltrap injection in India, it is recommended to Call/WhatsApp +91-9310090915 or send mail to info@indianpharmanetwork.in.

Can Zaltrap® be made available in SAARC countries? 

Apart from Gulf countries, Zaltrap® can be available in SAARC countries (Afghanistan, Bangladesh, India, Bhutan, Maldives, Nepal, Pakistan, and Sri Lanka). Indian Pharma Network (IPN) can help facilitate the supply of Zaltrap® injections in these countries, ensuring access to this therapeutic drug through legal and reliable channels.

What are the storage conditions of Zaltrap®?

Store the vials in a refrigerator at 2°C to 8°C (36°F to 46°F). Keep the vials of Zaltrap® in the original outer carton to protect them from light. Discard unused portion.

Is it safe to buy Zaltrap® online in India?

Yes, one can buy Zaltrap online in India at the lowest price from the Indian Pharma Network (IPN) if this medicinal product is not (yet) registered or available in their country. We can help facilitate the supply of Zaltrap® through legal channels.