Overview of Cholangiocarcinoma (CCA):
Cholangiocarcinoma (CCA) can also be addressed as Bile Duct Cancer. It is a very rare and aggressive carcinoma that develops in the bile ducts inside and around the liver. CCA is expected to account for about 3% of cancers in the gastrointestinal system.
Cholangiocarcinoma (CCA) is a difficult cancer to diagnose. CCA`s signs and symptoms are not specific, and many times the disease is not diagnosed until it has progressed when surgery may no longer be a therapeutic option. The recommended treatment option will directly depend on whether or not the disease has advanced or metastasized.
Treatment of Cholangiocarcinoma (CCA) with Tibsovo:
Commercially available for oral administration in 250 mg tablets, Tibsovo is the first treatment of its kind. Tibsovo 250 mg is a targeted therapy, designed to work against the mutation isocitrate dehydrogenase-1 (IDH1). In non-cancerous cells, the IDH1 gene creates the IDH1 protein, which significantly plays a role in normal chemical reactions within cells. When the isocitrate dehydrogenase-1 gene is altered because of a genetic mutation, cells create a mutated version of the isocitrate dehydrogenase-1. This mutated IDH1 (isocitrate dehydrogenase-1) protein may involve in promoting the development of certain kinds of cancers, including cholangiocarcinoma (CCA).
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