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Lymphoma is a certain kind of cancer that begins in infection-fighting cells of the immune system, called lymphocytes. When the white blood cell starts multiplying uncontrollably, these cells are in the lymph nodes, spleen, thymus, bone marrow, and other body parts. There are two types of Lymphoma i.e. 

  • Hodgkin’s Lymphoma and
  • Non-Hodgkin’s Lymphoma
Hodgkin’s Lymphoma
In Hodgkin’s Lymphoma, white blood cells within the lymphatic system, called lymphocytes, help protect you from germs and infections, grow abnormally and crowd out healthy white blood cells that tend to grow into a type of cell called B-lymphocytes. Hodgkin’s Lymphoma sums about 10% of Lymphomas. The types of Hodgkin’s Lymphoma are:
  • Classic Hodgkin’s Lymphoma
  • Nodular lymphocyte-predominant Hodgkin’s Lymphoma
Classic Hodgkin’s Lymphoma is further classified as:
  • Nodular sclerosis Hodgkin’s Lymphoma
  • Mixed cellularity Hodgkin’s Lymphoma
  • Lymphocyte-rich classic Hodgkin’s Lymphoma
  • Lymphocyte-depleted Hodgkin’s Lymphoma
Symptoms: Hodgkin’s Lymphoma
  • Fever
  • Fatigue
  • Trouble breathing
  • Chest pain 
  • Night sweats
Treatment and medications for Hodgkin’s Lymphoma:
Treatment of Hodgkin’s Lymphoma depends upon the stage of the disease. The treatment options are:
  • Radiation therapy
  • Chemotherapy
  • Targeted therapy
  • Bone marrow transplant
Non-Hodgkin’s Lymphoma 
Non-Hodgkin’s Lymphoma is more common than Hodgkin’s Lymphoma. The main difference between Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma(NHL) is a type of atypical cell called the Reed-Sternberg cell. This cell is only present in Hodgkin’s Lymphoma. Non-Hodgkin’s Lymphoma is categorized as: 
  • B-cell lymphoma or 
  • T-cell Lymphoma.
B-cell Lymphoma is a common NHL. The most common B-cell Lymphoma is diffuse large B-cell lymphoma, and follicular Lymphoma, and the least common B-cell Lymphoma are:
  • Burkitt’s Lymphoma
  • marginal zone B-cell lymphoma
  • lymphoplasmacytic Lymphoma
  • primary mediastinal large B-cell Lymphoma
  • Small lymphocytic Lymphoma
The most common kinds of NHL in children and teens are:
  • Anaplastic large cell lymphoma
  • Burkitt’s Lymphoma (small noncleaved cell lymphoma)
  • Diffuse large B-cell Lymphoma
  • Lymphoblastic Lymphoma
The most common kind of NHL in adults are:
  • Diffuse large B-cell Lymphoma
  • Follicular Lymphoma
Symptoms: Non-Hodgkin’s Lymphoma
 Common symptoms of Non-Hodgkin’s Lymphoma are:
  • swollen lymph nodes
  • fatigue
  • fever
  • night sweats
  • unexplained weight loss
  • abdominal pain or swelling
  • chest pain
  • rashes or skin lumps
 Non-Hodgkin’s Lymphoma (NHL) is a kind of blood cancer that develops and occurs in the lymphatic system. It develops from different white blood cells called B cells, T cells, or natural killer cells.
Treatment and medications for Non-Hodgkin’s Lymphoma
The treatment and medications depend upon the severity of the disease, and the healthcare professional will treat the patient of NHL according to the severity of the Lymphoma. Here are some treatment methods and medicines:
  • Chemotherapy: Platinum drugs, alkylating agents, purine analogs, corticosteroids, etc.
  • Radiation Therapy
  • Stem cell transplant
  • Immunotherapy: Monoclonal antibodies such as Zevalin, Adcetris, etc.
  • Targeted drug therapy
Commonly Asked Questions
What is the survival rate of patients with Non-Hodgkin’s Lymphoma?
The survival rate for patients with NHL depends on many factors such as age, type of NHL, stage at which NHL was diagnosed, and the response of NHL towards the treatment.
What is the most common Non-Hodgkin’s Lymphoma?
The most common Non-Hodgkin’s Lymphoma is B-cell Lymphoma (diffuse large B-cell Lymphoma and follicular Lymphoma).
Why do Non-Hodgkin’s lymphoma cells grow uncontrollably?
The exact reason behind the cause of Non-Hodgkin’s Lymphoma is unknown, but it is predicted that it could happen if a person has a medical condition that weakens your immune system, a person takes immunosuppressant medication, or person has previously been exposed to a common virus called the Epstein-Barr virus. 
What foods should one avoid with Non-Hodgkin’s Lymphoma?
One should take a balanced diet to avoid NHL. A study by Zheng showed that people who ate more of certain foods tended to have a lower risk of non-Hodgkin’s Lymphoma. These foods are tomatoes, broccoli, squash, cauliflower, onions, lettuce, apples, citrus fruits, etc. 
What are the treatments for Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma?
There are several treatments for Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma:
Chemotherapy medicines: ifosfamide (Ifex), oxaliplatin (Eloxatin), gemcitabine (Infugem), doxorubicin (Doxil), etc.
  • Radiation Therapy
  • Stem cell transplant
  • Immunotherapy: tafasitamab (Monjuvi), ibritumomab tiuxetan (Zevalin), brentuximab vedotin (Adcetris), alemtuzumab (Campath), polatuzumab vedotin (Polivy), etc.
How do I get brentuximab vedotin (Adcetris)?
Buy Brentuximab vedotin injection; Adcetris in India is a prescription-only drug but not yet approved for marketing in India. However, as per the Drugs and Cosmetic Act 1940 and Rules 1945, provisions exist for a patient’s personal import of unapproved drugs in India.
Indian Pharma Network is a pharmaceutical consulting company that assists Patients in preparing documentation for Name-Patient Medicine Import for their personal use. It facilitates such access only against valid prescriptions according to all local laws and regulations. Patients/ Clinicians / Researchers can write to – 
Nitin Goswami

Nitin Goswami joined us as an Editor in 2020. He covers all the updates in the field of Pharmaceutical, Business Healthcare, Health News, Medical News, and Pharma News.

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