Pegaspargase: A Chemotherapy for Acute Lymphoblastic Leukaemia

Background: Pegaspargase (Oncaspar) is a conjugate of monomethoxy polyethylene glycol and L-asparagine amidohydrolase, an asparagine specific enzyme. The L-asparaginase is a kind of an enzyme that catalyzes the conversion of the amino acid L-asparagine into ammonia and aspartic acid. The pharmacological outcome of agent pegaspargase is thought to be based on selective killing of leukemic […]

Soliris (Eculizumab Injection) Dosage, and Side Effects

Background: Soliris (Eculizumab Injection) is a medicine launched for the treatment of patients with paroxysmal nocturnal haemoglobinuria (PNH), generalised myasthaenia gravis (GMG), atypical haemolytic uraemic syndrome (aHUS), and neuromyelitis optica spectrum disorder (NMOSD). The medication is developed and manufactured by the US based pharmaceutical company Alexion Pharmaceuticals, a subsidiary of AstraZeneca. It was given orphan […]

Get to Know Your Adrenal Glands it’s Cancer

In the human body, adrenal glands basically sit at the top of the kidneys, one on each side, and have an inner core (called medulla) surrounded by an outer shell (called cortex). The inner medulla develops adrenaline, the “fight or flight” stress hormone. While the non-appearance of the adrenal medulla does not cause complications or […]